Before anyone had ever heard of single-use options in biomanufacturing, Parrish Galliher, the founder of the Xcellerex company, was determined that there had to be a better way to complete his customer projects than the clean-in-place, steam-in-place protocol used with his existing stainless steel manufacturing options. Left alone with a welding torch, a Big Green Egg grill, and his own devices, Galliher welded sides onto the grill, used a heat-sealing device to make his own bags, and fashioned a mixing mechanism on the bottom of the grill. The result? The first design for a disposable single bioreactor. After project completion, customers seemed interested in Galliher’s grill device and asked where they could purchase one. The results, they noticed were more efficient and, well, eggcellent, leading to the birth of the Xcellerex company.