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Moving viral vector manufacturing forward

From cell lines to GMP manufacturing and regulatory support, let’s work together to turn viral vector possibilities into progress

Turn viral vectors into vectors of hope

Every decision at every stage of viral vector development and manufacturing presents opportunities to drive speed, scalability, and success on the road to patients.

Whether you’re developing a gene therapy or viral vector-based vaccine, we help you address production challenges with proven technologies, services, and expertise that support your path from scientific possibility to meaningful progress.

Powering performance in upstream cell culture

Improve cell line stability and optimize growth conditions with solutions built for consistency from research to GMP manufacturing.

Cell lines for viral vectors

Explore CAP™ Ad and HEK-based transient and producer cell lines engineered for seamless progression across stages and backed by flexible licensing options.

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Cell culture media

Find off-the-shelf and custom culture media and supplements to support high-density, productive cell cultures at any scale.

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Single-use bioreactors

Scale without redesign using GMP-ready bioreactors designed to simplify operational growth and support process control for both suspension and adherent cultures.

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Driving downstream consistency

Deliver high-quality gene therapies and vaccines with curated purification strategies that protect product integrity, maximize yield, and support clinical and commercial success.

Clarification

Clarify with single-use filters and automated systems for depth filtration and more.
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Capture

Purify with scalable platforms and specially-engineered resins to capture viral vectors and support fast throughput.
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Ultrafiltration/diafiltration

Concentrate and formulate with closed tangential flow filtration (TFF) platforms and single-use flow kits that streamline processes and reduce handling.
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Buffer management

Save time and space with the right buffer management strategy, including inline conditioning.
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Fill and finish

Aseptic processing strategies designed to optimize recovery and support regulatory validation.
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Contamination control

Build a contamination control strategy aligned with the latest regulatory expectation.
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Innovation across viral vector platforms

Find technologies and workflow strategies for viral vector production that help you scale up, optimize yields, and align with regulatory expectations.

Adeno associated virus (AAV)

Lentivirus (LV)

Adenovirus (AdV)

In vivo gene replacement

Ex vivo and in vivo cell engineering

Vaccines and transient expression

Upstream

Reach large-scale AAV production using suspension cell cultures in scalable, single-use bioreactors without sacrificing process control.

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Upstream

Increase productivity of producer cells for LV production with a continuous production strategy that allows multiple vector harvests from a single batch.

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Upstream

Minimize replication-competent adenovirus during AdV production using a cell line and culture strategy engineered to limit impurity formation.

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Downstream

Efficiently separate full from empty capsids with over 80% viral genome recovery using innovative anion-exchange technology.

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Downstream

Improve LV recovery using a closed and scalable filtration strategy that replaces labor-intensive centrifugation processes.

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Downstream

Optimize your AdV purification with a salable two-step chromatography workflow.

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Explore the full AAV workflow

Explore the full LV workflow

Explore the full AdV workflow

Comprehensive support for your gene therapy journey

Process development services

Build robust viral vector processes and analytics to transform complex biology into a controlled, regulatory-ready operation.
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Regulatory consultation

Access guidance and digital technologies to help meet strict — and often evolving — requirements, including robust analytical and stability testing.
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Viral vector production training

Keep your workforce ahead of a fast-evolving landscape with education on the latest science, tools, and technology.
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Equipment services

Explore services that keeps your equipment compliant and running smoothly, including preventive maintenance, remote monitoring, and more.
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Read the latest insights on viral vector manufacturing

Scaling to tackle non-rare diseases

Hear from industry leaders on facility design strategies for viral vector manufacturing and the three most promising paths forward.

Navigating regulatory expectations

A regulatory expert shares her top suggestions for gene therapy developers preparing for the clinic and beyond.

Reducing costs for better access

Learn how to manage common cost drivers in viral vector and vaccine manufacturing to make treatments more accessible to those in need.

Frequently asked questions about viral vectors

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