Main session: Low molecular weight drug discovery and characterization
Main session: Characterization of biotherapeutics
Main session: Assessment of critical quality attributes of biotherapeutics
Workshops: SPR-based assays for comparability and potency assessment
Workshop: Use of SPR in process development of biotherapeutics
Workshop: Driving forward drug discovery with binding kinetics
Workshop: Small molecules as therapeutics: from structure-activity relationship to clinical trials
Optimization of a commercially available fragment library by identification of promiscuous binders by SPR using Biacore systems.
Binding kinetics by Surface Plasmon Resonance:
Insight into Structure-kinetics/thermodynamics relationships.
Biacore 8K – meeting the toughest challenges in screening and characterization
Biacore 8K efficiently delivers binding data with the quality you expect.
Specific protein quantification during cell culture and process development using surface plasmon resonance
Using the parallel configuration of Biacore 8K for efficient characterization of monoclonal antibodies
In this study, the possibilities of the parallel configuration of Biacore 8K for efficient reagent characterization was explored.
Biacore 8K+ for concentration analysis with throughput and precision
This poster presents the new software features in Biacore Insight Evaluation Software that supports concentration analysis with both serial and parallel calibration curves.
Development of a protein-protein interaction inhibition assay using Biacore 8K
Here we present a study to identify suitable candidates for inhibition of the interaction between Intrinsic Disordered Protein (IDP) X and protein Y.
Surrogate potency assays with SPR—two CQA determined in only one assay
We present how Biacore™ surface plasmon resonance (SPR)-based assays can be used as surrogate potency assays to facilitate comparability and biosimilar studies.
Why sensitivity matters: reliable hit characterization for challenging targets using high-sensitivity SPR systems
Here we present a study comparing the sensitivity of Biacore™ S200, Biacore T200, and Biacore 8K SPR systems.
Efficient assays with orientation-specific binding of antibodies
This poster presents three newly developed pre-immobilized sensor chips: Sensor Chip Protein A, Sensor Chip Protein G, and Sensor Chip Protein L.
Biacore 8K – kinetic possibilities in all directions
Binding kinetic studies with a Biacore system is feasible over a wide dynamic range, making it possible to determine the binding kinetic rate constants for basically all biological interactions.
Biacore Insight Evaluation Software for PLA and EC50 potency analysis
This poster presents new features in Biacore Insight Evaluation Software enabling PLA and EC50 curve analysis.
Facilitating IgG FcRn analyses
In the present study an assay setup combining biotin capture of FcRn with single-cycle kinetic analysis of the antibody interaction is described.