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April 13, 2016

Choosing a protein purification system

By Sara Lidblad, Product Manager at GE Healthcare

Investing in a protein purification system can be both exciting and overwhelming due to all the aspects that need to be considered. A purification system is expected to have a long life span, often a decade or more, and to deliver a solid performance year after year. To get the most out of the system, how can you be sure that nothing is overlooked in the purchase process?

System specification—is that all that needs to be considered?

Considering features that are required for the application in which the system is to be used is a good starting point when looking into system specifications. Flow rates, pressure range, types of monitors, and modes of sample injection are key features that need to be considered.

Should the method be run in a single step, or does the process require a higher level of automation, for example, to gain efficiency in multi-step purifications?

These are just some of the decisions that need to be made, but don’t worry. You are not alone as you consider these decisions. A good approach is to sit down with a specialist from your vendor and discuss your current and future application needs. A chromatography or applications specialist is able to translate your needs into system specifications.

My top consideration: support

So, system specifications to fit your applications are a must, but don´t forget about other important aspects that need to be thought of in the decision process. Be sure to consider if the system is supported with application trainings as well as scientific and customer support and service after the installation. Product support is crucial, not only in the initial transition phase, but also to ensure a long system life span. A secured availability of service and support will ensure that the investment delivers high value year after year.

Investing in an ÄKTA chromatography system from GE Healthcare is not only an investment in an excellent protein purification system. It is also an investment in access to extensive expertise for many years to come. At GE Healthcare, we have global, dedicated, and experienced teams of application specialists, service engineers, and scientists available to support in any situation that might arise, from application questions to trainings, to seminars, and so much more. With your ÄKTA system, you get a comprehensive solution with support in every aspect of your protein purification application.

Learn more about training and application support.

What do you think is important when considering the purchase of a chromatography system? Let me know by leaving a comment below.