HiScreen™ column with MabSelect™ VL protein L resin
HiScreen™ column with MabSelect™ VL protein L resin
Protein L resin in HiScreen™ columns for affinity capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain
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MabSelect™ VL protein L resin in HiScreen™ chromatography columns. A redesigned protein L ligand captures antibody Fabs, bispecifics, and other variants containing a kappa light chain with high binding capacity and improved alkaline stability.
- High dynamic binding capacity for efficient capture of target molecules.
- Stable when cleaned with 0.1 M NaOH, reducing risk for bioburden incidents.
- Provides good resolution for product-related impurities in the capture of bispecific antibodies.
Built for a diversifying pipeline
As the diversity of antibody variants increases, so does the need for chromatography resins that can capture and purify these variants. As an alternative to protein A, protein L resin can be used to capture antibody Fabs, bispecific antibodies, and other molecules containing kappa variants of the variable light (VL) chain. Protein L binds human kappa light chain subtypes 1, 3, and 4 and mouse kappa light chain subtype 1.
Read more| Product | Product Name | Price | ||
|---|---|---|---|---|
| 17542015 | HiScreen™ MabSelect™ VL | 1 × 4.7 mL | 1,329.00 USD |
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