Prepacked ReadyToProcess™ columns with MabSelect™ VL protein L resin. The redesigned protein L ligand provides high binding capacity and improved alkaline stability. For affinity capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain. MabSelect™ VL in ReadyToProcess™ columns is supplied made to order in 80 mm, 126 mm, 178 mm, 251 mm, 359 mm, and 450 mm column diameter sizes in different bed heights.

  • High dynamic binding capacity protein L resin for efficient capture of antibody Fabs, bispecifics, and variants containing a kappa light chain.
  • Stable when cleaned with 0.1 M NaOH, reducing risk for bioburden incidents.
  • Provides good resolution for product-related impurities in the capture of bispecific antibodies.
  • ReadyToProcess™ columns with robust design and validated column packing methods for consistent performance.

Built for a diversifying pipeline

As the diversity of antibody variants increases, so does the need for chromatography resins that can capture and purify these variants. As an alternative to protein A, protein L resin can be used to capture antibody Fabs, bispecific antibodies, and other molecules containing kappa variants of the variable light (VL) chain. Protein L binds human kappa light chain subtypes 1, 3, and 4 and mouse kappa light chain subtype 1.

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Product Product Name Price
17542066 ReadyToProcess™ MabSelect™ VL NS, 32 L (450/200) 32 L On Request

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