MabSelect™ VL protein L minicolumns with a redesigned protein L ligand. Capture antibody Fabs, bispecifics, and other variants containing a kappa light chain with high binding capacity and improved alkaline stability.

  • Supports high-throughput chromatography process development (HTPD) and scale-up by allowing parallel screening of chromatographic conditions using a minicolumn format and robotic workstation.
  • High-throughput workflow allows investigation of enlarged experimental workspace for better process understanding.
  • Prefilled with MabSelect™ VL resin with high dynamic binding capacity for efficient capture of target molecules provides good resolution for product-related impurities in the capture of bispecific antibodies.

Built for a diversifying pipeline

As the diversity of antibody variants increases, so does the need for chromatography resins that can capture and purify these variants. As an alternative to protein A, protein L resin can be used to capture antibody Fabs, bispecific antibodies, and other molecules containing kappa variants of the variable light (VL) chain. Protein L binds human kappa light chain subtypes 1, 3, and 4 and mouse kappa light chain subtype 1.

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Product Product Name Price
17542034 PreDictor™ RoboColumn® MabSelect™ VL, 600 µL 600 µL 378.00 USD Add to cart

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17542033 PreDictor™ RoboColumn® MabSelect™ VL, 200 µL 200 µL 378.00 USD Add to cart

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