Novel core bead technology and multimodal ligand give Capto Core 400 dual functionality, size exclusion and binding chromatography, in one chromatography resin.

• For intermediate purification and polishing of viruses and other large biomolecules (M_r > 350 000) in flowthrough mode.
• Novel core bead technology allows efficient capture of contaminants, while target molecule is collected in the flowthrough.
• Significantly improved productivity and higher flow rates compared with gel filtration methods.
• Straightforward optimization due to flowthrough chromatography and robust performance.
• Convenient small-scale purification, process development, and scale-up using prepacked HiTrap and HiScreen columns.