MabSelect SuRe pcc protein A resin is an affinity chromatography resin for purification of monoclonal antibody and Fc-fusion proteins. The high resin capacity at short residence times makes it an excellent choice for periodic counter-current chromatography in monoclonal antibody (mAb) purification. The alkaline-stable, recombinant protein ligand allows for efficient resin cleaning.
- High dynamic binding capacity (e.g., ~ 60 g IgG/L resin at 2.4 min residence time).
- High productivity through capture of large mass of monoclonal antibody in a short period of time.
- Covered by a comprehensive security of supply program, including dual sources of the agarose base matrix and protein A ligand.
Resin cleaning advantage
The alkali-stabilized, protein A-derived ligand gives the resin greater stability than conventional protein A-based resins under the alkaline conditions used in cleaning-in-place (CIP) protocols. Consequently, the possibility of cleaning with cost-effective reagents such as sodium hydroxide (NaOH) will improve process economy. In addition, the use of NaOH for cleaning efficiently inactivates bacteria, mold, and yeast, with improved product quality as a result.
Read moreProduct | Product Name | Price | ||
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17549105 | MabSelect SuRe pcc, 10 L | 10 L | On Request |
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17549104 | MabSelect SuRe pcc, 5 L | 5 L | On Request |
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17549101 | MabSelect SuRe pcc, 25 mL | 25 mL | 3 599.53 USD |
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17549102 | MabSelect SuRe pcc, 200 mL | 200 mL | 6 868.25 USD |
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17549103 | MabSelect SuRe pcc, 1 L | 1 L | 23 517.56 USD |
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