MabSelect SuRe pcc protein A resin is an affinity chromatography resin for purification of monoclonal antibody and Fc-fusion proteins. The high resin capacity at short residence times makes it an excellent choice for periodic counter-current chromatography in monoclonal antibody (mAb) purification. The alkaline-stable, recombinant protein ligand allows for efficient resin cleaning.

  • High dynamic binding capacity (e.g., ~ 60 g IgG/L resin at 2.4 min residence time).
  • High productivity through capture of large mass of monoclonal antibody in a short period of time.
  • Covered by a comprehensive security of supply program, including dual sources of the agarose base matrix and protein A ligand.

Resin cleaning advantage

The alkali-stabilized, protein A-derived ligand gives the resin greater stability than conventional protein A-based resins under the alkaline conditions used in cleaning-in-place (CIP) protocols. Consequently, the possibility of cleaning with cost-effective reagents such as sodium hydroxide (NaOH) will improve process economy. In addition, the use of NaOH for cleaning efficiently inactivates bacteria, mold, and yeast, with improved product quality as a result.

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Product Product Name Price
17549101 MabSelect SuRe pcc, 25 mL 25 mL On Request Get Quote
17549102 MabSelect SuRe pcc, 200 mL 200 mL On Request Get Quote
17549103 MabSelect SuRe pcc, 1 L 1 L On Request Get Quote
17549104 MabSelect SuRe pcc, 5 L 5 L On Request Get Quote
17549105 MabSelect SuRe pcc, 10 L 10 L On Request Get Quote

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