By combining the high-flow characteristics of Capto™ resin with a small particle size, Capto™ SP ImpRes delivers excellent pressure-flow properties with impressive resolution. The ability to run at higher flow rates and higher bed heights also increases flexibility in process design.

Suits large-scale purification processes

Capto™ SP ImpRes is a BioProcess™ chromatography resin developed for large-scale purification of biopharmaceutical proteins. Based on the well-established Capto™ base matrix and with traditional ionic group ligands, it provides many opportunities for improved productivity and straightforward process development.

Prepacked columns and other formats

Capto™ SP ImpRes resin is available in the following formats: 

Process development scale: prepacked

• PreDictor™ filter plates, 96-well plates for high-throughput screening or process development.
• PreDictor™ RoboColumn™ units, miniaturized columns for high-throughput process development.
• HiScreen™ columns, optimized for method and process development.
• Validation columns, scale-down columns for robust and reproducible process validation and process development (Tricorn™ format)
• f(x) columns, precalibrated chromatography column for fast and accurate mechanistic modeling during downstream process development.

Lab scale: prepacked for manual purification

HiTrap™ columns, for easy use with a syringe, peristaltic pump, or chromatography system.

Lab scale: prepacked for automated purification and analysis

HiTrap™ columns, for easy use with a syringe, peristaltic pump, or chromatography system.

Process characterization: resin kits

Process Characterization Kit, designed for studying the potential impact that resin ligand density might have on the process outcome.

Process-scale purification: prepacked

ReadyToProcess™ columns, 1 L and larger columns for clinical manufacturing that minimize the need for cleaning and cleaning validation.