The high selectivity of the anion multimodal ligand allows operation in a variety of process conditions to solve challenging purification problems. Contaminants such as DNA, host cell proteins, leached protein A, aggregates, and viruses are efficiently removed.

Prepacked columns and other formats

Capto adhere ImpRes resin is available in the following formats: 

Process development scale: prepacked

• PreDictor Capto adhere ImpRes filter plates, 96-well plates for high-throughput screening or process development.
• PreDictor Capto adhere ImpRes RoboColumn™ units, miniaturized columns for high-throughput process development.
• HiScreen Capto adhere ImpRes columns, optimized for method and process development.

Lab scale: prepacked for manual purification

HiTrap Capto adhere ImpRes columns, for easy use with a syringe, peristaltic pump, or chromatography system.

Lab scale: prepacked for automated purification and analysis

HiTrap Capto adhere ImpRes columns, for easy use with a syringe, peristaltic pump, or chromatography system.

Process characterization: resin kits

Process Characterization Kit Capto adhere ImpRes, designed for studying the potential impact that resin ligand density might have on the process outcome.

Process-scale purification: prepacked

ReadyToProcess Capto adhere ImpRes columns, 1 L and larger columns for clinical manufacturing that minimize the need for cleaning and cleaning validation.