Sera-Mag Oligo(dT)-Coated Magnetic Particles

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Sera-Mag Oligo(dT)-Coated Magnetic Particles enable mRNA isolation and extraction for applications such as RT-PCR, cDNA library construction, cDNA microarrays, affinity purification, primer extension, and subtractive hybridization.

Encapsulation means no exposed iron and minimized interference with downstream enzymatic applications
Covalently bound oligo(dT)14 prevents leaching from the particle surface
Very high, specific poly A+ binding capacity ensures maximum extraction of mRNA
Fast reaction kinetics increase throughput and precision, also enabling faster movement through viscous solutions
Uniform, nominal 1 μm diameter provides high surface area and excellent lot-to-lot reproducibility
Also available as custom-manufactured magnetic beads

Convenient and efficient mRNA isolation

Eukaryotic mRNA makes up only 1 to 3% of total cellular RNA, so efficient mRNA purification is critical. Sera-Mag Oligo(dT) Magnetic Particles remove 90% or more of mRNA from total RNA with just one extraction. Sera-Mag Oligo(dT) Magnetic Particles bind target mRNA through pairing of the polyadenylated RNA tail found on the 3’ end of mRNA to the covalently bound oligo(dT) groups on the surface of the particles. This binding is easily accomplished using standard hybridization conditions during the mRNA purification process.

Fast magnetic response times and stable physical integrity

The core of the particle is made by a free radical emulsion polymerization of styrene and acid monomer. One layer of magnetite is coated onto this core, while the surface is modified to minimize non-specific binding of proteins. Oligo(dT) groups are then covalently bound to the particle surface. Since the magnetite is encapsulated, there is no exposed iron minimizing interference with downstream enzymatic applications.

Customized magnetic bead solutions that fit seamlessly into your workflows can be developed for specific applications, often saving you time and money. This product can be provided ready-to-use with little or no need for further modification allowing you to focus on your research. To learn more, please visit our custom manufacturing services page.

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Product	Product Name	Pack size All 5 mL 1 1 mL 100 mL	Price
38152103011150	Sera-Mag Oligo (dT) Coated Magnetic particles	1 mL	152.07 USD	Add to cart Get Quote In Stock Stock on request Limited stock
38152103010350	Sera-Mag Oligo (dT) Coated Magnetic particles	100 mL	3 491.00 USD	Add to cart Get Quote In Stock Stock on request Limited stock
38152103010150	Sera-Mag Oligo (dT) Coated Magnetic particles	5 mL	575.00 USD	Add to cart Get Quote In Stock Stock on request Limited stock
29373490	Buy Three Sera-Mag Oligo(dt) packs and get TempliPhi	1	2 054.00 USD	Add to cart Get Quote In Stock Stock on request Limited stock
29373492	Buy Three Sera-Mag Oligo(dt) packs and get MagRack 6	1	2 091.00 USD	Add to cart Get Quote In Stock Stock on request Limited stock
29373486	Buy Three Sera-Mag Oligo(dt) packs and get GenomiPhi	1	1 980.00 USD	Add to cart Get Quote In Stock Stock on request Limited stock

Sera-Mag Oligo(dT)-Coated Magnetic Particles

Convenient and efficient mRNA isolation

Fast magnetic response times and stable physical integrity

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