This high-affinity streptavidin (SA) sensor chip immobilizes biotinylated molecules for surface plasmon resonance (SPR) interaction analysis on Biacore systems.

  • Versatile: immobilizes biotinylated peptides, proteins, nucleic acids, or carbohydrates
  • Ready-to-use: streptavidin is pre-immobilized, ready for fast, high-affinity ligand capture
  • Robust: streptavidin-biotin is one of the strongest non-covalent interactions in nature
  • Non-covalent: a convenient alternative for ligands refractory to covalent immobilization
  • Standardized ligand orientation: controlled biotinylation enables oriented capture

Streptavidin-biotin capture

Sensor Chip SA provides a surface of streptavidin covalently attached to a carboxymethyldextran matrix. Dissociation of biotinylated ligands from the surface of the chip is generally negligible during the course of a Biacore analysis because the affinity of streptavidin for biotin is extremely high, with an equilibrium dissociation constant of about 10-15 M. High binding capacity, reproducibility, and chemical resistance give excellent performance over a broad range of applications. The surface of Sensor Chip SA is resistant to 1-minute pulses of many agents commonly used in SPR sensor chip washing and regeneration protocols (Table 1).

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Product Product Name Price
29104992 Series S Sensor Chip SA, pack of 1 1 sensor chip 455.00 USD Add to cart Get Quote

In Stock Stock on request Limited stock

BR100032 Sensor Chip SA, pack of 3 3 sensor chips 776.00 USD Add to cart Get Quote

In Stock Stock on request Limited stock

BR100398 Sensor Chip SA, pack of 1 1 sensor chip 290.00 USD Add to cart Get Quote

In Stock Stock on request Limited stock

BR100531 Series S Sensor Chip SA, pack of 3 3 sensor chips 906.00 USD Add to cart Get Quote

In Stock Stock on request Limited stock

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