Biacore Insight Extended Screening and Characterization Extension

Biacore Insight Extended Screening and Characterization Extension provides additional software tools for screening of low molecular weight (LMW) fragments using Biacore Insight Evaluation Software. For Biacore 8K+, Biacore 8K, Biacore T200, and Biacore S200 SPR systems.

Characterize a wider range of compound-target interactions using additional kinetic fitting models and evaluation settings.
Evaluate challenging interactions such as LMW fragment binding to transmembrane G-protein-coupled receptors (GPCRs) and bivalent protein interactions with enhanced support.
Dedicated software tools for screening of LMW fragments to speed up assay setup and streamline evaluation.

Efficiently analyze challenging interactions

The software contains dedicated software tools for affinity and kinetics screening of LMW compounds and fragments. It speeds up assay setup and streamlines evaluation, providing greater flexibility and tools to analyze complex biomolecular interactions such as characterization of G-protein coupled receptor (GPCR) binding, bivalent analytes, ion channels, and more.

Choice of fitting models and application templates shortens time to results

The extension offers a wider variety of fitting models using maximum response (Rmax) control and Blank subtraction, giving access to more customization options.

The extension also has three application templates—Clean screen, Binding level screen, and Affinity screen. These evaluation methods guide the user and shorten time to results for the entire SPR workflow in fragment-based drug discovery (FBDD).

Floating e-licensing for enhanced flexibility

Biacore Insight Evaluation Software and extensions introduce floating licenses to allow sharing of access rights between users and computers. Electronically secure a machine license for one computer, or a concurrent license for networks. Time-limited licenses let you scale the number of licenses needed for more flexibility.