An exceptionally versatile chip for SPR interaction analysis

Sensor Chip CM5 is the most versatile and widely used dextran-based chip, suitable for most general-purpose surface plasmon resonance (SPR) applications. Carboxymethyl surface chemistry supports the study of many different types of ligands and binding partners–from small organic molecules, such as drug candidates, through to large molecular assemblies and even whole viruses. High binding capacity gives a high response, advantageous for capture assays and for interactions involving small molecules. High surface stability provides accuracy and precision, and allows repeated analysis on the same surface.

Application examples include:

FBDD-based screening for novel drugs against Hepatitis C virus (HCV)

Surface plasmon resonance-based determination of adenovirus concentration on Biacore T200

Sensor chip formats for Biacore systems

Biacore sensor chips are available in two formats:

• “S series” sensor chips are for use with Biacore 8K+, Biacore 8K, Biacore S200, Biacore T200, and Biacore 4000 SPR systems.
• Sensor chips not designated with “S series” are designed for Biacore X100, Biacore 3000 and Biacore C SPR systems.