High chemical resistance and mechanical strength

One of the major applications for the PTFE membrane is the clarification of corrosives, solvents, and aggressive fluids. This includes the important requirement in HPLC analysis for sample filtration where any solid particles can cause permanent damage to the column. The 0.5 µm pore size is normally used.

Air and gas sterilization* make use of the hydrophobic characteristics of PTFE membrane filters and their ability to stop aqueous aerosols. Pore sizes of 0.2 µm and 0.5 µm are typically used. Sterile* venting of vacuum manifolds, fermentation vessels, and filtrate tanks and containers utilize PTFE 0.2 µm membranes.

Looking for a filter paper, membrane filter, or syringe filter? Let Cytiva help you find the optimal filter for your needs to ensure reliable analysis.

*Refers to sterilization by filtration for small sample use which is an industry term for filters of pore size 0.2 um or smaller as referenced in guidance such as EPA Guidance for Industry Sterile Drug Products Produced by Aseptic Processing — Current Good Manufacturing Practice Section IX, Part B (September 2004).