Good column packing is essential for any chromatographic process and plays a key role in the large-scale commercial manufacture of biopharmaceuticals. Robust and verified packing and testing methods help eliminate concerns and risks associated with poorly packed beds.
There is more to chromatography than the column. The ÄKTA systems support our columns throughout scales. Easy buffer management can also be integrated to the process. Different levels of automation are available through UNICORN software and DeltaV™ Distributed Control System.
Manufacturing biopharmaceuticals demands very high hygiene standards. Minimizing manual handling through closed systems is one way to address this. Sanitization is another important consideration. For chromatography, success will depend on column design and the power of the sanitizing solutions.