Single use solutions | Cytiva, formerly GE Healthcare Life Sciences

Past, present, and future of single-use bioprocessing

Over the years single-use technologies have evolved to become a mainstream approach for achieving productivity. From single-use bioreactors and disposable chromatography columns, to complete single-use workflows and biomanufacturing facilites , Cytiva has been at the forefront of single-use innovation. This transformation has been, and will continue to be, driven by collaboration with biomanufacturers and other industry experts.

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A strategy for success

Adding a piece of single-use equipment is a step in the right direction of achieving higher productivity. But successful implementation of a widespread single-use biomanufacturing strategy requires a comprehensive approach. Based on GE’s decades of experience in biomanufacturing, a successful strategy encompasses these 4 pillars.

Technical – develop scientific knowlege and experience
Operational – secure and streamline implementation
Economic – understand initial and ongoing financial impact
Strategic – develop flexible solutions with collaboration

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Leverage the latest know-how

Single-use technologies offer opportunities to develop robust biomanufacturing processes quickly. Achieving this goal requires knowledge – of materials, equipment and consumables, processes, and how they work together.

Process intensification applies this knowledge to reduce costs and improve process yields. Working with experienced technical experts can help you achieve these goals the first time.

Consider the impact on operations

Thinking about the key operational needs when implementing single-use technologies can pave the way for business success and efficiency. Consider these questions:

Will manufactured products meet quality and regulatory requirements?
Is the supply chain secure?
What should be considered when designing a single-use biomanufacturing facility?
Can it be integrated with existing automation?
What is the environmental impact?

Look at the economics

Single-use technology is more cost-effective than traditional stainless steel methods in some situations. But economics are only one factor. Considering key variables will help guide your decision about which technology makes sense for your specific business objective.

View the study: single-use vs. stainless steel

Plan for the future

Devise your biomanufacturing strategy to work for the short- and long- term. Implementing scalable processes will help you future-proof your business.

Considerations for capacity expansion
Expanding overseas? – Prefabricated biopharma facilities cut construction and installation time
Case study: How did Fujifilm Diosynth expand capacity?

RELATED INFORMATION

Read insights from biopharmaceutical manufacturers and industry thought leaders on single-use technology. Download the e-book - Evolve with flexibility: Advancing single-use technology with industry collaboration.
Learn how to make bioprocessing faster, more efficient, and economical – view Cytiva’s single-use portfolio for the bioprocess spectrum.

RELATED SERVICES

Collaborate with our biomanufacturing services team to expedite your time to market – learn more about Fast Trak bridge manufacturing services.
Resolve biomanufacturing challenges for upstream and downstream process efficiency at every stage of development with Fast Trak process development services.
Discover how Cytiva helps ensure single-use equipment compliance and suitability for regulatory requirements.
Improve productivity and solve bioprocessing problems with hands-on training, learn more about Fast Trak training and education courses.
Learn how Cytiva’s extractables and leachables policy aligns with the BPOG protocol.

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