Compare the system specifications of our single-use chromatography systems

ÄKTA ready™ 450
Compact system for small-scale manufacturing with a low hold-up volume and flow rate		 ÄKTA™ ready
Robust single-use chromatography system with isocratic or gradient capability for process scale-up and manufacturing		 ÄKTA ready™ variable UV
Single-use system with a three-wavelength UV sensor and a single-use pH sensor. Supports processing of viral vectors and nucleic acids		 ÄKTA ready™ extended
Comprehensive single-use chromatography system providing flexibility in process scale-up and manufacturing applications		 ÄKTA ready™ XL
High-capacity system to support your purification needs in manufacturing
Footprint (W × H × D) 640 × 940 × 558 mm 1000 × 1650 × 800 mm (isocratic) and
1160 × 1650 × 800 mm (gradient)		 1140 × 1670 × 840 mm 1060 × 1760 × 1000 mm 1295 × 1920 × 1215 mm
Weight 110 kg 230 kg (isocratic) and 250 kg (gradient) 258 kg 360 kg 685 kg
Operating max. pressure 4 bar
Inlets 8+4 6+1 6+6 6+4
Outlets 6
UV Simultaneous, 3-wave lengths 280 nm Simultaneous, 3-wave lengths
pH Single use, integrated Optional to use traditional electrode Single use, integrated
Flow kit flow range 5-450 mL/min High flow kit: 7.5–510 L/h
Low flow kit: 3–175 L/h		 ¾ inch i.d.:
Range: 45–1900 L/h
1-inch i.d.
Range: 90-3500 L/h
Flow rate accuracy ± 6% of actual value, or ±12 mL/min, whichever is greater High flow kit: 
± 5% actual value at flow‡ ≥ 40 L/h
± 10% actual value at flow < 40 L/h
Low flow kit: 
± 5% actual value at flow‡ ≥ 20 L/h
± 10% actual value at flow < 20 L/h		 ¾ inch i.d.:
Accuracy, ±5 L/h or 2% whichever is greater
1-inch i.d.:
Accuracy, ±5 L/h or 2% whichever is greater
Connectors Tri‑Clamp™ and AseptiQuik® Tri‑Clamp™, ReadyMate™ and AseptiQuik® Tri‑Clamp™ and AseptiQuik®. ReadyMate™ available on request Tri‑Clamp™, ReadyMate™ and AseptiQuik® Tri‑Clamp™ and AseptiQuik®
BioPhorum (BPOG) Extractables Protocol Yes
Pressure sensor Range: 0.1–4 bar
Accuracy: ± 0.1 bar, or ± 5% of actual value		 Range: 0–5 bar g
Accuracy: ± 0.20 bar g		 Range: 0.1–4 bar
Accuracy: ± 0.1 bar, or ± 5% of actual value
Temperature sensor Range: 2°C to 30°C.
Accuracy: ± 1°C		 Range: 2°C to 40°C
Accuracy: ± 3°C		 Range: 2°C to 30°C.
Accuracy: ± 2°C
Conductivity sensor Range: 1–200 mS/cm
Accuracy: ± 5% of actual value		 Range: 0–150 mS/cm
Accuracy: ± 5% full scale		 Range: 1–200 mS/cm
Accuracy: ± 0.5 mS/cm, or ± 7% of actual value
UV sensor Range: 0–2 AU*
Accuracy: linearity ± 2%		 Range: 0.01–1.0 AU
Accuracy: linearity ± 5%		 Range: 0–2 AU.
Accuracy: linearity ± 2%
pH sensor Range: 3–10
Accuracy: ± 0.3		 Range: pH 2–12
Accuracy: ± 0.2 pH at calibration temperature		 Range: 3–10
Accuracy: ± 0.3
Material compliance USP <88> Class VI Test for biocompatibility 
Animal free or complies with the conditions in EMA/410/01
Human-Machine Interface (HMI) Stand alone
 Integrated with the system
Control software UNICORN™ 7.0.2 or higher UNICORN™ 7.0.2 or higher, or Figurate powered with Emerson DeltaV™

* Valid for 250–700 nm, 2% linearity 0–1 AU for 206–250 nm.
‡ Valid for liquid with density of water and 1.0 to 1.3-fold the viscosity of water at the actual liquid temperature; and max temperature difference of 10°C between liquid and ambient temperature.

 

Flow kits and software solutions designed for your single-use chromatography system