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Lateral-flow immunoassay development

Optimizing rapid point-of-care test development for immunodiagnostic applications

Advancement of lateral-flow assays

Advancement of lateral-flow assays

The simplicity, ease-of-use, and low cost of lateral flow assays (LFAs) are drivers for the continued growth of this type of rapid test. Requiring a specialized set of membranes and pads, including a sample pad or blood separator, conjugate release pad, nitrocellulose membrane, and absorption pad, research groups continue to optimize the sensitivity of POC testing. Many lateral flow immunoassays have been developed for a wide range of analytes including biomarkers for cardiac failure, cancer, infectious diseases, and foodborne pathogens and toxins. Modification of nitrocellulose membranes and the addition of signal amplification pads have successfully improved test sensitivity.

With you every step of the assay

Interactive brochure: With you every step of the assay

Using a single supplier for multiple components across a lateral flow test and one who can also support your workflow from idea and prototype to commercialization can help streamline your activities and accelerate assay development and commercialization. Here's how we can help!

Considerations for membrane selection

Infographic: Considerations for membrane selection

Remind yourself of the key considerations for membrane selection to meet your goals for test sensitivity, specificity, and duration no matter your choice of reagents, sample, or application.

10 top tips for lateral flow assay development

Checklist: 10 top tips for lateral flow assay development

When designing your own lateral flow assay, there are several variables to consider including choice of detection reagents, assay materials, and manufacturing methods. Use this checklist to review ten important considerations when developing your LFA, which we hope will give you a deeper insight into lateral flow assays to streamline your development process.