Nucleic Acid Isolation Kits for cfDNA

Sera-Xtracta™ Virus/Pathogen Kit*

DNA and RNA isolation from bacteria and viruses including COVID-19 with rapid, 30 minute protocol and reproducible yields.
*For research use only (RUO). Not for diagnostic use.

Sera-Xtracta™ HMW DNA Kit*

High yield extraction of high-molecular-weight DNA from blood, buffy coat, saliva, cultured cells and tissue samples with minimal co-purification of RNA.
*For research use only (RUO). Not for diagnostic use.

Sera-Xtracta™ Cell-Free DNA Kit*

Efficient purification of cfDNA from liquid biopsy including plasma, serum and urine. Selects for small-fragment cfDNA while minimizing genomic DNA contamination.
*For research use only (RUO). Not for diagnostic use.

Scientists in Lyo-Lab, wide angle, action shot (high res)

E-book: Optimizing results from nucleic acid isolation

Addressing the challenges and highlighting approaches to accelerate and optimize DNA and RNA extraction from a variety of common sample types including liquid biopsy.

New application note: Detection of cancer-associated mutations in liquid biopsies for the identification of therapeutic targets

The effective capture of highly fragmented cfDNA and minimized co-purification of higher molecular weight DNA increases the probability of detecting mutations that constitute a minor proportion of genetic alterations present in the tumor. The Sera-Xtracta Cell-Free DNA Kit provides efficient extraction of the main cfDNA peak, reduction in gDNA carry-over, and increased recovery of small fragments.

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NEW white paper: Investigating cell-free DNA in liquid biopsy

Cell-free DNA (cfDNA) is currently trending as a biomarker from liquid biopsy in several clinical applications, including oncology, organ and transplant medicine, and non-invasive prenatal testing (NIPT). Due to the small amount of cfDNA found in circulation, there is a need to use efficient, highly sensitive technologies, such as NGS, to detect these biomarkers. This white paper discusses the challenges and opportunities in measuring cfDNA from liquid samples.

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Accelerating NGS sample preparation

Recent years have seen the development and adaptation of several approaches to NGS sample preparation, aiming to improve speed, throughput, and reproducibility. Many of these approaches are also compatible with automation, providing the opportunity to minimize human error, variation and bottlenecks, and further improve consistency between samples from different batches.

Next generation sequencing sample preparation workflow

Webinar: Nucleic acid isolation for molecular diagnostics–from sample to NGS analysis

While the manual, column-based approach to nucleic acid extraction is still widely used, scientists under pressure from high-throughput demands are turning their attention to superparamagnetic beads. Magnetic bead DNA extraction is automation friendly and well-suited to a range of applications, including sample preparation for next-generation sequencing (NGS). Find out about the pros and cons of each technique, and the selection process depending on sample type, throughput requirements, targets, and other factors in our webinar.

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Guide: Nucleic acid isolation

DNA isolation (and RNA isolation) is the first step for many modern genomics techniques and applications, which require high-quality starting material free of contaminants. The choice of approach depends on several factors, including the target DNA, source organism, the type and quality of starting material, and the application. This guide suggests products and solutions for optimizing the steps in the nucleic acid isolation process.

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Get your free sample kit

Discover a better way of isolating nucleic acids with a free Sera-Xtracta™ sample kit. The HMW and Cell-Free DNA sample kits are sufficient for processing 8 × 200 µL whole blood samples. The Virus/Pathogen sample kit is suitable for processing up to 96 samples dependent on sample type and input volume. Just let us know a bit about your application and we’ll send a kit your way.

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Sera-Xtracta™ Cell-Free DNA KitSera-Xtracta™ HMW DNA KitSera-Xtracta™ Virus/Pathogen Kit

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Optimize nucleic acid isolation in molecular biology applications

Sera-Xtracta™ Virus/Pathogen Kit*

Sera-Xtracta™ HMW DNA Kit*

Sera-Xtracta™ Cell-Free DNA Kit*

E-book: Optimizing results from nucleic acid isolation

New application note: Detection of cancer-associated mutations in liquid biopsies for the identification of therapeutic targets

NEW white paper: Investigating cell-free DNA in liquid biopsy

Accelerating NGS sample preparation

Webinar: Nucleic acid isolation for molecular diagnostics–from sample to NGS analysis

Guide: Nucleic acid isolation

Unraveling the challenges of nucleic acid isolation

Choosing and using magnetic beads

Guide to next-generation sequencing (NGS)

Whitepaper: NGS technologies—trends and applications

Get your free sample kit

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