Magnetic separation with Sera-Mag technology

Protein and peptide single-pot solid-phase-enhanced sample preparation (SP3) with Sera-Mag SpeedBead Carboxylate-Modified Magnetic Particles is a novel technique that takes advantage of the bead features to enable the fast and efficient removal of a wide range of detergents, salts and other contaminants from protein and peptide samples prior to mass spectrometry analysis. This protocol has been developed by Joseph D. Card, Guillaume Adelmant, and Jarrod A. Marto of the Dana-Farber Cancer Institute Inc., Brigham and Women’s Hospital, and Harvard Medical School, MA, USA. [This note is not and should not be construed as an endorsement of any product.]

Magnetic beads (or superparamagnetic particles) are versatile little tools for easy and effective isolation of biomolecules. Use this guide to compare the different surface chemistries and find the type for your application.

Sera-Mag superparamagnetic particles are characterized by fast magnetic response time. For labs that process high volumes of samples, where speed is of the essence, Sera-Mag SpeedBeads are preferred. SpeedBeads have a double layer of magnetite for even faster magnetic response time.

You get fast results with Sera-Mag particles and SpeedBeads, without compromising on performance. You can count on your assays to deliver consistent results time after time. Good monodispersity with uniform bead size is the key to consistent performance.

Sera-Mag particles and SpeedBeads come in a range of formats including Carboxyl, Streptavidin, Neutravidin™, Amino and Oligo (dT).

If you need something different, our dedicated Customized Solutions Team is here to help, including specific conjugations, buffer formulations, format changes and lyophilization.