FAQ
SeraSil-Mag beads are silica coated superparamagnetic particles for nucleic acid isolation and diagnostic extraction applications, for sample types including biofluids and liquid biopsy, when small or trace amounts of DNA are available. They provide an optimal surface for DNA binding with high performance and low background.
Not in theory. However, every type of nucleic acid will require specific buffers and an optimized method.
The presence of beads in the extracted DNA could create artifacts or inhibit the downstream tests. It is recommended to ensure the complete collection of the SeraSil-Mag beads during the elution step.
The response time depends on the magnetic field generated by the magnet. For instance, the separation time of SeraSil-Mag beads is ~5 seconds for 5 mL of suspension (concentration 20 mg/mL) via SepMag™ Biomagnetic Separator. This assures a very fast magnetic response during the assay and an advantage for automation.
Yes. When automating, pay attention to the settling time and employ intermittent mixing if necessary.