FAQ

Spare parts

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# Product Name Product Code Price
1 STM O-Ring Set, silicone 56410690 37.88 USD Add to cart
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2 91 mm (3") TC-Gasket, silicone 11000525 206.00 USD Add to cart
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3 Clamp 91 mm TC 56410671 192.97 USD Add to cart
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Accessories

The use of a permeate flow control is strongly recommended during upstream clarification of target material. Permeate flow control rate is dependent on the process flux (LMH) and surface area.

For permeate flow control you need a permeate pump kit. For information regarding permeate pump kit for GrandStand 450 (GSM450PERPRP) and for GrandStand 550 (GSM550PERPRP) see below.

 

Accessories for STM cartridges that have to be ordered separately

Housing for STM cartridges:

Housing assembly for 35 STM cartridges (56-4106-27)

Housing assembly for 55 STM cartridges (56-4106-28)

Steaming-in-place connections:

Basic SIP system connection for a single cartridge (28-4004-44)

Permeate side inlet and outlet connections needed for each additional cartridge installed on GrandStand 550 (28-4004-45)

To blank off permeate ports of the cartridge:

Blank off cap 50 mm TC incl gasket, stainless steel (44-7135-01)

Clamp 50 mm TC, stainless steel (12-4100-30)

To blank off the drain port of the cartridge, when stored off the system:

Blank off cap 25 mm TC incl gasket, stainless steel (18-1001-25)

Clamp 25 mm TC, stainless steel (12-4100-31)

To blank off the feed and retentate ports of the cartridge, when stored off the system:

Blank off cap 50 mm TC incl gasket, stainless steel (44-7135-01)

Clamp 50 mm TC, stainless steel (12-4100-30)

 

Please note that the item numbers are not necessarily in sequential order.


When stored off the system, store the cartridge with storage solution using blank off cap, gasket and clamp for each port.

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# Product Name Product Code Price
1 Housing Assembly for 35STM Cartridges 56410627 6 471.00 USD Add to cart
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1 Housing Assembly for 55STM Cartridges 56410628 7 083.00 USD Add to cart
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3 Clamp 50 mm (1") TC 12410030 15.39 USD Add to cart
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3 Clamp 50 mm (1.5") TC (Toggle Clamp) 56410669 75.77 USD Add to cart
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7 TC-Gasket 51 mm i.d. 10 mm, EPDM 18101288 189.42 USD Add to cart
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7 Blind Flange, 51 mm TC 44713501 101.82 USD Add to cart
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10 Gasket 25 mm, i.d. 6 mm 18001927 15.42 USD Add to cart
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10 Blind Flange, including gasket, 25 mm 18100125 76.96 USD Add to cart
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11 Clamp 25 mm TC 56410665 156.27 USD Add to cart
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91 mm (3") TC-Gasket, silicone 11000525 206.00 USD Add to cart
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Clamp 91 mm TC 56410671 192.97 USD Add to cart
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Accessories for STM cartridges have to be ordered separately.

 


Housing for STM cartridges

Housing assembly for 35 STM cartridges (56-4106-27)

Housing assembly for 55 STM cartridges (56-4106-28)

 

TC clamps and gaskets for the drain, feed, retentate and permeate ports:

Clamp 25 mm TC (56-4106-65)

Gasket 25 mm i.d. 13 mm (0.5 inch) in silicone (56-4109-94) or EPDM (18-0200-00)

Clamp 50 mm TC (44-7134-01)

Gasket 50 mm i.d. 38 mm (1.5 inch) in silicone (56-4109-96) or nitrile (56-4109-97)

 

To blank off the drain, feed, retentate and permeate ports:

Blank off cap 25 mm TC incl gasket (18-1001-25)

Clamp 25 mm TC (56-4106-65)

Blank off cap 50 mm TC incl gasket (44-7135-01)

Clamp 50 mm TC (44-7134-01)

 

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# Product Name Product Code Price
1 Clamp 25 mm TC 56410665 156.27 USD Add to cart
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2 Gasket, 25 mm, i.d. 12 mm 18020000 30.84 USD Add to cart
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2 Gasket 25 mm (0.5") TC i.d. 13 mm, silicone 56410994 75.77 USD Add to cart
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4 Gasket 50 mm (1.5") TC i.d. 38 mm, silicone 56410996 88.79 USD Add to cart
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4 50 mm (21.5") TC-Gasket, Buna-N 56410997 75.77 USD Add to cart
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5 Blind Flange, including gasket, 25 mm 18100125 76.96 USD Add to cart
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5 Blind Flange, 51 mm TC 44713501 101.82 USD Add to cart
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6 Clamp, 50 mm TC, SS 44713401 10.68 USD Add to cart
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9 91 mm (3") TC-Gasket, silicone 11000525 206.00 USD Add to cart
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10 Clamp 91 mm TC 56410671 192.97 USD Add to cart
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11 Housing Assembly for 35STM Cartridges 56410627 6 471.00 USD Add to cart
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12 Housing Assembly for 55STM Cartridges 56410628 7 083.00 USD Add to cart
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Troubleshooting

Find solutions to product related issues. For unlisted issues please contact local Cytiva service representation.

General Advice for Troubleshooting when Using Cross Flow Filters

Please check the following items during troubleshooting:

Samples volume and system working volume have been used in calculations of concentration factor and diafiltration beforehand.

Process settings of Membrane Capacity, Flux, Shear (or volumetric cross flow rate) have been properly applied for both sample characteristics and membrane pore size or NMWC designation.

Filter is properly wetted before use (also make sure that there is no air lock in the filters created by condensation on microfiltration membranes as a result of incorrect autoclave settings).

Ensure CFF filters are properly wetted before starting processing. This may be tested against new cartridge “Clean Water Flux Test or against the water flux specifications in the Certificate of Quality. Microfitlration membranes are shipped dry and are rewetted with water or buffer. Hollow fiber ultrafiltration membranes are shipped in glycerol wetting preservative. These filters may require 15-20% alcohol/water solution to restore wetting or remove glycerol. Flat sheet cassette ultrafiltration devices (for example, KvickLab and KvickFlow Cassettes) are shipped in a solution of NaOH/Glycerol which must be flushed out before use.

Prior to using cassettes, make sure the single gasket is in the correct position in the holding device and that the cassette(s) within are oriented properly in the holder.

Check integrity of cassette system using water under pressure on retentate side to 1 barg to check for leaks in the seal of the cassette with the stainless steel holding device.

Check to see that cartridges or cassettes that have been previously used are checked for integrity (air diffusion or bubble point tests) and for cleanliness (normalized Clean Water Permeability before processing).

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