FAQ

Accessories

The use of a permeate flow control is strongly recommended during upstream clarification of target material. Permeate flow control rate is dependent on the process flux (LMH) and surface area. 

For permeate flow control you need a permeate pump kit. Detailed information regarding permeate pump kit for GrandStand 450 (GSM450PERPRP) and for GrandStand 550 (GSM550PERPRP) is found below.

Permeate side connections are not included with the GrandStand system. Please attach only light weight plastic fittings to the permeate side. To prevent possible damage to the cartridge, do not attach stainless steel valves directly to the permeate port.

To blank off the permeate, feed and retentate ports of the cartridge, when stored off the system:

Blank off cap 50 mm TC in stainless steel incl. gasket (44-7135-01)

Blank off cap 50 mm TC in plastic (56-4109-90)

Clamp 50 mm TC in stainless steel (12-4100-30) or plastic (56-4106-68)

Gasket o.d. 50 mm i.d. 38 mm, 1.5 inch (12-4100-34)

 

Please note that the item numbers are not necessarily in sequential order.


When stored off the system, store the cartridge with storage solution using blank off cap, gasket and clamp for each port.

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# Product Name Product Code Price
3 Clamp 50 mm (1") TC 12410030 15.52 USD Add to cart
3 Clamp 50 mm TC 56410668 78.66 USD Add to cart
3 Clamp 50 mm (1.5") TC (Toggle Clamp) 56410669 78.66 USD Add to cart
7 TC-Gasket 51 mm i.d. 10 mm, EPDM 18101288 205.00 USD Add to cart
7 Blind Flange, 51 mm TC 44713501 109.71 USD Add to cart
7 50 mm (1.5") TC Blank-Off Cap, polysulfone 56410990 89.01 USD Add to cart
8 50 mm (1.5") TC 13 mm (0.5") Barb 56410986 135.58 USD Add to cart
8 50 mm TC i.d. 38 mm (1.5") 19 mm (0.75"ch) Barb 56410987 135.58 USD Add to cart

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Scope of Supply for GrandStand 550 with one SIP1 and two SIP2 installed (this would be supplied by one GSMSIPSIP2KIT, code no 28-4004-44, plus one GSMSIP2KIT, code no 28-4004-45). Light Blue dashed lines: original basic system battery, Black and Green lines: original basic system components; Dark Blue lines: GSMSIPSIP2KIT and GSMSIP2KIT. Magenta lines: by customer. Element “F” at the top of the drawing refers to hydrophobic sterile vent filter assembly (not included).

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The use of a permeate flow control is strongly recommended during upstream clarification of target material. Permeate flow control rate is dependent on the process flux (LMH) and surface area.

For permeate flow control you need a permeate pump kit. Detailed inforation regarding permeate pump kit for GrandStand 450 (GSM450PERPRP) and for GrandStand 550 (GSM550PERPRP) is available below.

Accessories for MSM cartridges that have to be ordered separately.

Housing for MaxCell MSM cartridges:

Housing assembly for 45 MSM cartridges with straight adaptors (56-4106-31)

Housing assembly for 65 MSM cartridges with straight adaptors (56-4106-32)

Housing assembly for 85 MSM cartridges with straight adaptors (56-4106-33)

To blank off permeate ports of the cartridge:

Blank off cap 50 mm TC incl gasket, stainless steel (44-7135-01)

Clamp 50 mm TC, stainless steel (12-4100-30)

To blank off the drain port of the cartridge, when stored off the system;

Blank off cap 25 mm TC incl gasket, stainless steel (18-1001-25)

Clamp 25 mm TC, stainless steel (12-4100-31)

To blank off the feed and retentate ports of the cartridge, when stored off the system:

Blank off cap 64 mm TC, plastic (56-4109-92)

Clamp 64 mm TC (12-4100-28)

Gasket 64 mm i.d. 51 mm, 2 inch (12-4100-33)

 

Please note that the item numbers are not necessarily in sequential order.


When stored off the system, store the cartridge with storage solution using blank off cap, gasket and clamp for each port.

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# Product Name Product Code Price
3 Clamp 50 mm (1") TC 12410030 15.52 USD Add to cart
3 Clamp 50 mm (1.5") TC (Toggle Clamp) 56410669 78.66 USD Add to cart
6 TC-Gasket 51 mm i.d. 10 mm, EPDM 18101288 205.00 USD Add to cart
6 Blind Flange, 51 mm TC 44713501 109.71 USD Add to cart
10 4" TC Gasket, silicone 11000527 181.12 USD Add to cart
10 Housing Assembly for 45MSM Cartridges 56410631 9,094.00 USD Add to cart
10 Housing Assembly for 65MSM Cartridges 56410632 10,100.00 USD Add to cart
10 Housing Assembly for 85MSM Cartridges 56410633 11,500.00 USD Add to cart
11 Gasket 25 mm, i.d. 6 mm 18001927 18.97 USD Add to cart
11 Blind Flange, including gasket, 25 mm 18100125 82.80 USD Add to cart
12 Clamp 25 mm TC 56410665 161.46 USD Add to cart

The use of a permeate flow control is strongly recommended during upstream clarification of target material. Permeate flow control rate is dependent on the process flux (LMH) and surface area.

For permeate flow control you need a permeate pump kit. For information regarding permeate pump kit for GrandStand 450 (GSM450PERPRP) and for GrandStand 550 (GSM550PERPRP) see below.

 

Accessories for STM cartridges that have to be ordered separately

Housing for STM cartridges:

Housing assembly for 35 STM cartridges (56-4106-27)

Housing assembly for 55 STM cartridges (56-4106-28)

Steaming-in-place connections:

Basic SIP system connection for a single cartridge (28-4004-44)

Permeate side inlet and outlet connections needed for each additional cartridge installed on GrandStand 550 (28-4004-45)

To blank off permeate ports of the cartridge:

Blank off cap 50 mm TC incl gasket, stainless steel (44-7135-01)

Clamp 50 mm TC, stainless steel (12-4100-30)

To blank off the drain port of the cartridge, when stored off the system:

Blank off cap 25 mm TC incl gasket, stainless steel (18-1001-25)

Clamp 25 mm TC, stainless steel (12-4100-31)

To blank off the feed and retentate ports of the cartridge, when stored off the system:

Blank off cap 50 mm TC incl gasket, stainless steel (44-7135-01)

Clamp 50 mm TC, stainless steel (12-4100-30)

 

Please note that the item numbers are not necessarily in sequential order.


When stored off the system, store the cartridge with storage solution using blank off cap, gasket and clamp for each port.

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# Product Name Product Code Price
1 Housing Assembly for 35STM Cartridges 56410627 6,999.00 USD Add to cart
1 Housing Assembly for 55STM Cartridges 56410628 7,661.00 USD Add to cart
3 Clamp 50 mm (1") TC 12410030 15.52 USD Add to cart
3 Clamp 50 mm (1.5") TC (Toggle Clamp) 56410669 78.66 USD Add to cart
7 TC-Gasket 51 mm i.d. 10 mm, EPDM 18101288 205.00 USD Add to cart
7 Blind Flange, 51 mm TC 44713501 109.71 USD Add to cart
10 Gasket 25 mm, i.d. 6 mm 18001927 18.97 USD Add to cart
10 Blind Flange, including gasket, 25 mm 18100125 82.80 USD Add to cart
11 Clamp 25 mm TC 56410665 161.46 USD Add to cart
91 mm (3") TC-Gasket, silicone 11000525 213.00 USD Add to cart
Clamp 91 mm TC 56410671 209.00 USD Add to cart

The use of a permeate flow control is strongly recommended during upstream clarification of target material. Permeate flow control rate is dependent on the process flux (LMH) and surface area.

For permeate flow control you need a permeate pump kit. For information regarding permeate pump kit for GrandStand 450 (GSM450PERPRP) and for GrandStand 550 (GSM550PERPRP) see below.

Accessories for MaxCell cartridges that have to be ordered separately:

Straight connector kit (56-4107-37)

Straight connector (RBMX-16PS-ST)

Two different wrench set available:

MaxCell standard wrench set (56-4107-39)

MaxCell wrench set with applied torque (56-4107-40)

Permeate side connections are not included with the GrandStand system. Please attach only light weight plastic fittings to the permeate side. To prevent possible damage to the cartridge, do not attach stainless steel valves directly to the permeate port.

To blank off the permeate ports of the cartridge:

Blank off cap 50 mm TC in stainless steel incl. gasket (44-7135-01)

Blank off cap 50 mm TC in plastic (56-4109-90)

Clamp 50 mm TC in stainless steel (12-4100-30) or plastic (56-4106-68)

Gasket o.d. 50 mm i.d. 38 mm, 1.5 inch (12-4100-34)

To blank off retentate and feed ports of cartridge, when stored off the system:

Blank off cap 64 mm TC, plastic (56-4109-92)

Clamp 64 mm TC (12-4100-28)

Gasket o.d. 64 mm i.d. 51 mm, 2 inch (12-4100-33)

 

Please note that the item numbers are not necessarily in sequential order.


When stored off the system, store the cartridge with storage solution using blank off cap, gasket and clamp for each port.

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# Product Name Product Code Price
3 Clamp 50 mm (1") TC 12410030 15.52 USD Add to cart
3 Clamp 50 mm TC 56410668 78.66 USD Add to cart
3 Clamp 50 mm (1.5") TC (Toggle Clamp) 56410669 78.66 USD Add to cart
6 TC-Gasket 51 mm i.d. 10 mm, EPDM 18101288 205.00 USD Add to cart
6 Blind Flange, 51 mm TC 44713501 109.71 USD Add to cart
6 50 mm (1.5") TC Blank-Off Cap, polysulfone 56410990 89.01 USD Add to cart
7 50 mm (1.5") TC 13 mm (0.5") Barb 56410986 135.58 USD Add to cart
7 50 mm TC i.d. 38 mm (1.5") 19 mm (0.75"ch) Barb 56410987 135.58 USD Add to cart
9 MaxCell O-Ring Set 56410692 76.83 USD Add to cart
9 Straight connector for MaxCell cross flow cartridge 56410726 140.42 USD Add to cart
9 Straight Adapter Kit for MaxCell Cartridge 56410737 342.00 USD Add to cart
9 Elbow Adapter Kit for MaxCell Cartridge 56410738 495.00 USD Add to cart
Standard Wrench Set for MaxCell Cross Flow Cartridge 56410739 520.00 USD Add to cart
Wrench Set with Applied Torque for MaxCell Cross Flow Cartridge 56410740 1,125.00 USD Add to cart

Accessories for running Kvick Flow cassettes that have to be ordered separately. Two Kvick Flow manual cassette holders are needed per adaptor kit.

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# Product Name Product Code Price
1 Kvick Flow Manual Cassette Holder 11000667 15,100.00 USD Add to cart
Clamp 50 mm (1") TC 12410030 15.52 USD Add to cart

Modular kits enhance flexibility of GrandStand systems to meet the needs of process development and process manufacturing groups. These modules may be added to the base system for your specific application at time of original purchase; or when process requirements change, the modules can provide the necessary system upgrade without requiring purchase of a completely new system. 

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# Product Name Product Code Price
Kvick Flow Manual Cassette Holder 11000667 15,100.00 USD Add to cart
Clamp 50 mm (1") TC 12410030 15.52 USD Add to cart

The use of a permeate flow control is strongly recommended during upstream clarification of target material. Permeate flow control rate is dependent on the process flux (LMH) and surface area.

For permeate flow control you need a permeate pump kit. For information regarding permeate pump kit for GrandStand 450 (GSM450PERPRP) and for GrandStand 550 (GSM550PERPRP) see below.

 

Accessories for SMO cartridges that have to be ordered separately

Housing for SMO cartridges:

Housing assembly for 35 SMO cartridges (56-4106-29)

Housing assembly for 55 SMO cartridges (56-4106-30)

Steaming-in-place connections:

Basic SIP system connection for a single cartridge (GSMSIPSIP2KIT)

Permeate side inlet and outlet connections needed for each additional cartridge installed on GrandStand 550 (GSMSIP2KIT)

To blank off permeate ports of the cartridge:

Blank off cap 50 mm TC (stainless steel) incl. gasket (44-7135-01)

Clamp 50 mm TC, stainless steel (12-4100-30)

To blank off the drain port of the cartridge, when stored off the system:

Blank off cap 25 mm TC incl gasket, stainless steel (18-1001-25)

Clamp 25 mm TC, stainless steel (12-4100-31)

To blank off the feed and retentate ports of the cartridge, when stored off the system:

Blank off cap 50 mm TC incl gasket, stainless steel (44-7135-01)

Clamp 50 mm TC, stainless steel (12-4100-30)

 

Please note that the item numbers are not necessarily in sequential order.


When stored off the system, store the cartridge with storage solution using blank off cap, gasket and clamp for each port.

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# Product Name Product Code Price
1 Housing Assembly for 35SMO Cartridges 56410629 7,178.00 USD Add to cart
1 Housing Assembly for 55SMO Cartridges 56410630 7,862.00 USD Add to cart
3 Clamp 50 mm (1") TC 12410030 15.52 USD Add to cart
3 Clamp 50 mm TC 56410668 78.66 USD Add to cart
3 Clamp 50 mm (1.5") TC (Toggle Clamp) 56410669 78.66 USD Add to cart
7 TC-Gasket 51 mm i.d. 10 mm, EPDM 18101288 205.00 USD Add to cart
7 Blind Flange, 51 mm TC 44713501 109.71 USD Add to cart
12 Gasket 25 mm, i.d. 6 mm 18001927 18.97 USD Add to cart
12 Blind Flange, including gasket, 25 mm 18100125 82.80 USD Add to cart
13 Clamp 25 mm TC 56410665 161.46 USD Add to cart
Clamp 91 mm TC 56410671 209.00 USD Add to cart

The use of a permeate flow control is strongly recommended during upstream clarification of target material. Permeate flow control rate is dependent on the process flux (LMH) and surface area.

For permeate flow control you need a permeate pump kit. Detailed information regarding permeate pump kit for GrandStand 450 (GSM450PERPRP) and for GrandStand 550 (GSM550PERPRP) available below.

 

Accessories for ProCell cartridges that have to be ordered separately.

Housing for ProCell cartridges:

Housing assembly for 152 M cartridges (56-4106-35)

Housing assembly for 154 M cartridges (56-4106-36)

To blank off the permeate port of the cartridge:

Blank off cap 50 mm TC (stainless steel) incl. gasket (44-7135-01)

Clamp 50 mm TC, stainless steel (12-4100-30)

To blank off retentate and feed ports of cartridge, when stored off the system:

Blank off cap 64 mm TC, plastic (56-4109-92)

Clamp 64 mm TC, stainless steel (12-4100-28)

Gasket o.d. 64 mm i.d. 51 mm, 2 inch (12-4100-33)

 

Please note that the item numbers are not necessarily in sequential order.


When stored off the system, store the cartridge with storage solution using blank off cap, gasket and clamp for each port.

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# Product Name Product Code Price
1 Housing Assembly for ProCell 152M Cartridges 56410635 11,200.00 USD Add to cart
1 Housing Assembly for ProCell 154M Cartridges 56410636 11,600.00 USD Add to cart
3 Clamp 50 mm (1") TC 12410030 15.52 USD Add to cart
3 Clamp 50 mm TC 56410668 78.66 USD Add to cart
3 Clamp 50 mm (1.5") TC (Toggle Clamp) 56410669 78.66 USD Add to cart
6 TC-Gasket 51 mm i.d. 10 mm, EPDM 18101288 205.00 USD Add to cart
6 Blind Flange, 51 mm TC 44713501 109.71 USD Add to cart
7 50 mm (1.5") TC 13 mm (0.5") Barb 56410986 135.58 USD Add to cart
7 50 mm TC i.d. 38 mm (1.5") 19 mm (0.75"ch) Barb 56410987 135.58 USD Add to cart
Clamp 6 inch 56410674 642.00 USD Add to cart

Spare parts

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The picture shows GrandStand 550 but GrandStand 450 is similar.

Screen gasket for GrandStand 450 (12-4100-38)

Screen gasket for GrandStand 550 (12-4100-39)

TC clamps and gaskets for the drain port, feed, retentate and permeate lines of your filter device:

To identify the size of clamps and gaskets needed for your hollow fiber cartridge or cassette holder, see the accessories sections Running cartridges or Running cassettes for your specific filter.

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# Product Name Product Code Price
6 Clamp 50 mm (1") TC 12410030 15.52 USD Add to cart

Troubleshooting

Find solutions to product related issues. For unlisted issues please contact local Cytiva service representation.

Shaft seals leak

Fluid supply inadequate for pump

No flow, but pump turns

General advice for troubleshooting manual filtration systems

For Manual Filtration Systems (QuixStand, FlexStand, GrandStand, etc.), please check the following during troubleshooting:


Power supply is suitable for running system. Please ensure that mains power supply FlowTech LabTop Rotary Lobe Pumps (used in FlexStand, KvickLab and KvickFlow Systems) is unprotected power.

Do not allow any large hard particles to enter the fluid path, as this will seize (gall) the internal machined surfaces of the pump head. A 50-mesh screen (“y-strainer with removable screen basket) is recommended.

Flow to inlet of rotary lobe pumps is not blocked. Also ensure that there is a gravity head pressure or other means to deliver process fluid to the pump head, as these rotary lobe pumps do not have suction lift capability.

Tank outlet valve is open and the recirculation loop is not blocked. Also check that the flow diameter is not restricted or becomes more narrow than that of the flow diameter at the inlet side of the pump. Finally make sure that the flow rates required can be delivered by the diameter of tubing or pipe used in the systems

Samples volume and system working volume have been used in calculations of concentration factor and diafiltration beforehand

Process settings of Membrane Capacity, Flux, Shear (or volumetric cross flow rate) have been properly applied for both sample characteristics and membrane pore size or NMWC designation.

For peristaltic pump-driven systems make sure the correct tubing sizes and polymers match the manufacturer’s required specifications for that pump head.

Make sure that peristaltic tubing is replaced regularly to avoid excessive wear or tubing failure.

Capacity too low, but pump turns

Pump is noisy

Rotors gall, pump seizes

Motor is overheated

Contact