Lyo-Stable custom stabilization service

What is lyophilization?

Lyophilization, also known as freeze-drying or cryo-desiccation, is the process of removing water from a sample without the need to apply heat, to stabilize the sample. Besides increasing sample shelf life, freeze-drying samples also reduces sample weight and volume, reduces the risk of contamination and eliminates the need to refrigerate samples, decreasing shipping and storage costs.

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Webinar: Eliminate temperature sensitivity with lyophilization technology

Join Amy Webster to discuss the technology and benefits of Cytiva’s Lyo-Stable™ service and how it's been used in high throughput manufacturing of temperature stable tests, to address the ongoing demand from the coronavirus pandemic for COVID-19 detection.

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Eliminate temperature sensitivity with lyophilization technology

Lyo-Stable – promoting sustainability

As well as increasing shelf life, lyophilization also helps to minimize environmental impact:

Individual components of an assay can be combined in a single tube, reducing packaging volumes and weight
Ability to store at room temperature means energy is not consumed through refrigeration/freezer storage
Reduced weight and volume make lyophilized samples more environmentally friendly for shipping
No dry or wet ice needed for transportation reducing environmental effects

The benefits of lyophilization in assay kit development

As well as increasing shelf life, lyophilizing samples reduces the weight and volume, helping cut down on shipping costs and environmental impact. Find out about the stabilization process and the many benefits of this technology in our knowledge article.

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Lyo-Lab video tour

Welcome to our new state-of-the-art lab facility dedicated to Lyo-Stable. The lab offers a scalable manufacturing solution whether you’re a start-up or an established global of stabilized molecular diagnostic kits.

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Our Lyo-Stable technology

Our patented lyophilization technology stabilizes individual proteins and reagents, as well as complete multiplex assays, by providing a molecular environment that protects against conformational changes in protein structure.

Your made-to-order cake or bead will contain our proprietary excipient mix to stabilize your temperature sensitive assay for storage and shipping at ambient temperature. All you need to add is your sample and you are ready-to-go!

Find out about the benefits to be gained from lyophilization

Benefits of lyophilization in molecular and immunodiagnostics

When you partner with Cytiva’s you get access to a wide selection of high performance, customizable components and solutions for immunoassay and molecular diagnostic applications. Our innovative stabilization technologies enable the design and manufacture of diagnostic kits that don’t require refrigeration during shipping and storage, helping you reach more patients at point of care.

Find out how lyophilization can benefit your diagnostic assays

Helping you build a smarter diagnostic assay

Our capabilities

Our analytical experience, combined with state-of-the-art instrumentation and stabilization technology, ensures precise control of the product as it progresses through manufacturing, resulting in a product that meets the highest standards and specifications. Batch-to-batch reproducibility is an important characteristic of each product we manufacture.

We have two flexible manufacturing technologies that are tailored to low and high throughput, and can manage batch sizes of 10k – 300k. On-site quality control technologies include moisture analysis, glass transition temperatures, QPCR, RT-PCR and sequencing.