BSL-2 manufacturing facilities
Rapidly add viral vector production capacity with expandable end-to-end solutions. KUBio and KUBio box include single-use processing lines, integrated automation, and proven processing support and expertise.
Optimize upstream and downstream efficiency while reducing operational costs. Configure FlexFactory platforms to meet specific process requirements, and easily scale up or out as your requirements change.
Other gene therapy solutions
Products, case studies, and support for process development and manufacturing of plasmids and vectors.
AAV vector collaboration
News: Cobra Biologics, GE, and Centre for Process Innovation collaborate to advance gene therapy. Innovate UK funding supports development of scalable, cost-effective AAV production.
China lab supports gene therapy
Blog: A new lab in Shanghai is offering much-needed industrial support for cell and gene therapies. Process development, manufacturing, and training services in China.
- Xcellerex XDR platform – single-use, stirred-tank bioreactors for cell cultivation up to 2000 L
- ReadyToProcess WAVE 25 bioreactor – single-use, rocking bioreactor for growing cells up to 25 L
- HyClone media and reagents – for cell growth, transfection, and buffer preparation
- Xcellerex mixers – single-use mixers for media and buffer preparation
- Single-use bags and connectors – to make aseptic connections between single-use components
- ULTA NFF filters – single-use capsules for harvest, clarification, and final filtration
- ReadyToProcess TFF filters – single-use cartridges for concentration
- ÄKTA tangential flow filtration systems – range of single-use filtration systems from benchtop to GMP production
- ÄKTA chromatography systems – range of automated systems from benchtop to GMP production
- Anion exchange resins and columns – for virus purification
- ReadyToProcess Adsorber Q – single-use anion exchange membranes for virus purification
- Capto Core 700 resin and columns – combines size exclusion and binding properties for lentivirus purification
- Capto Core 400 resin and columns – for intermediate purification and polishing
- Capto AVB resin and columns – affinity purification of AAV, with ligand derived from single-chain antibody
- Heparin Sepharose – heparin-based affinity purification of AAV
- Size exclusion resins and columns – for virus purification and analysis
- Xcellerex XDR microbial system – single-use, stirred-tank fermentor for growing plasmid-containing microbial cultures
- Capto PlasmidSelect resin and columns – to purify supercoiled plasmid DNA
- Cytodex microcarriers – for growing adherent cells in suspension culture
- Viral vector brochure
- Collaboration on improving adeno-associated virus manufacturing
- China lab supports cell and gene therapy with PD and other services
- KUBio BSL-2 manufacturing facility
- Going viral: How a new factory-in-a-box is helping scale up manufacturing of viral vector- based therapies to reach more patients