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The ÄKTA pure™ chromatography system is a flexible and intuitive platform designed for protein, peptide, and nucleic acid purification at various scales. It supports multiple chromatography techniques, including affinity, size exclusion, ion exchange, hydrophobic interaction, and reversed-phase chromatography. Key features include:

• Flow rates: Ranges vary by model, e.g., 0.001–25 mL/min (ÄKTA pure 25 M) or up to 150 mL/min (ÄKTA pure 150 L).
• Operating pressure: Up to 20 MPa (2900 psi) for some models.
• UV detection: 190–700 nm wavelength range.
• pH stability: Operational range of 2–12; CIP range of 0–14.
• Pump type: Piston pump, metering type.
• Upgradeable options: Multiple sample injection, buffer selection (up to 14 inlets), and multistep purification.

Applications span microgram to gram scales, with microliter-scale capabilities in the ÄKTA pure micro model.