SPR principles

Surface plasmon resonance (SPR) – Principle

Biacore systems

Biacore SPR systems

Empowering the study of interactions involving virtually any molecule, helping you to generate decisive affinity, kinetics, concentration, specificity, and comparability data, from research to drug discovery and quality control.

Drug discovery at the University of Dundee

See how University of Dundee has applied technologies to fully characterize the interaction between a drug and challenging targets like G-protein coupled receptors.

Biacore 8K SPR System: first impressions from scientists

Biacore T200: push the limits of interaction analysis

Biacore assay versus Single Radial Immunodiffusion assay

The Biacore T200 flu vaccine assay works with low dose vaccines without interference from oil-based adjuvants.

Access GoldSeal and upgrade your Biacore system

Short movie outlining GE’s GoldSeal program for refurbishment/remanufacturing of Biacore systems with upgraded hardware and software.

Biacore applications

Surface plasmon resonance (SPR) in drug development

SPR using Biacore systems is a key technology for drug candidate screening and characterization.

Value of binding kinetics in drug discovery

A scientist's view on the importance of binding kinetics using Biacore T200 in the development of chemotherapeutics.

Understanding target-compound interactions with SPR

Biacore SPR technology for biosimilar characterization

Using SPR for structure-function relationship studies

Florida State University uses a Biacore system for quantitative measurement of micromolar interactions.

How-to videos

Biacore 8K SPR system: Product overview

Enjoy this video tour of the major functions of Biacore 8K, a single solution for interaction analysis in both screening and characterization.

Biacore 8K SPR system tutorial: Fragment screening

Biacore 8K and Binding Level Screen is used to efficiently identify promising fragment hits based on binding level and binding behavior.

Biacore 8K SPR system tutorial: Assay development

Biacore 8K SPR system tutorial: Kinetics screening

Biacore S200: Clean Screen software workflow

Biacore S200 provides dedicated software support for fragment screening.

Biacore S200: Binding Level Screen software workflow

Biacore S200 provides dedicated software support for fragment screening.

Biacore S200: Affinity Screen software workflow

Biacore S200 provides dedicated software support for fragment screening.

Biacore S200: Competition using the ABA-inject software workflow

Biacore S200 provides dedicated software support for fragment screening.

Biacore S200: Kinetics software workflow

How to get started with Biacore T200

Sensorgram comparison evaluation workflow: Biacore T200 Software v3.0

How to get started with Biacore X100

Biacore X100 is designed for small-scale interaction analysis.