Mixing system: Wand Mixer
Mixing biocontainer: 200 L Mixer biocontainer
Application mixing type: Liquid-liquid
The Wand Mixer is a compact and non-invasive single-use mixing system. The heart of this system is a mixing biocontainer incorporating an innovative top-mounted impeller capable of providing efficient mixing for powder-liquid and liquid-liquid mixing applications.
The impeller comprises a rotating wand inside an inert polymer sleeve, and is designed to ensure low particle shedding and total containment while serving effectively in a wide variety of mixing tasks.
Introduction
High-viscosity materials can present a formidable mixing challenge, yet they also serve to illustrate the relative strengths and weakness of different mixing technologies. In this experiment, a Wand Mixer was used to perform liquid-liquid mixing in a highly viscous matrix—high fructose corn syrup 90% at a viscosity of 1200 centipoise (cP).
Materials and methods
A 200 L Wand Mixer mixing biocontainer was filled with 200 L of ADM Cornsweet 90 high fructose corn syrup (HFCS90), and mixing speed was set to 250 rpm. A 60 mL aliquot of dilute sodium hydroxide solution (8 M NaOH) was then added, via a top-mounted inoculation port, to the surface of the HFCS90. Solution homogeneity was monitored via a pH sensor mounted in the top of the biocontainer.
Results
Figure 1 shows solution homogeneity in the biocontainer during mixing. After the NaOH addition, mixing was found to be complete within approximately 5 min.
Fig 1. Shows solution homogeneity in the biocontainer during mixing.
Conclusions
The Wand Mixer can perform effectively at viscosities up to 1200 cP. For mixing applications < 200 L maximum volume, the 5 min mixing time in this experiment makes the Wand Mixer an excellent choice when high-viscosity liquid-liquid mixing is the primary intended purpose.
CY59908