Single-use mixing systems

Single-use bioprocessing equipment uses disposable components designed for one-time use — unlike stainless steel components, which are meant to be used multiple times, with cleaning between cycles. Single-use mixers are increasingly used in upstream bioprocessing and in benchtop cell culture. Their “plug-and-play” construction helps save time, and the ready-to-use, disposable components such as mixer bags help reduce the risk of contamination.

What's a single-use mixer?

Single-use mixing systems allow biomanufacturers to implement the use of disposable technology, such as single-use disposable bioreactors and mixer bags that were previously reserved for stainless steel equipment. These solutions allow the efficient mixing of pharmaceutical ingredients and preparing process solutions such as cell culture media and buffers.

Other bioprocesses that can be performed using single-use equipment include buffer preparation, cell harvesting, filtration, purification, and virus inactivation. These solutions support tanks of varying sizes.

Single-use mixing systems offer several benefits over their stainless steel counterparts, including reduced cleaning and sterilization requirements, potential cost savings, ease of use, and a decreased risk of cross-contamination. They come in varying designs with different specifications to meet your needs.

Consider process volume, size, and mixing technology when choosing a single-use mixer system. Disposable mixing applications can adapt to various applications and conditions, and their increased flexibility makes them convenient.

Single-use mixer FAQs

What are the benefits of single-use technology?

Benefits of single-use bioprocessing include:

1. Reduced costs: Single-use bioprocessing systems have the benefit of lowering costs by eliminating the need for sterilization, maintenance, and cleaning of stainless-steel bioreactors.
2. Increased productivity: Single-use bioprocessing has been shown to boost output because it eliminates the need for sterilizing processes in manufacturing, reducing the associated costs and simplifying automation. Since single-use systems use less water and chemicals than traditional stainless-steel hardware systems, they allow easy large-scale production.
3. Saving time: Single-use mixers are advantageous because they facilitate rapid production and minimize infrastructure requirements. This cuts down on the time it takes to get everything ready, set up, validate, and record results.
4. Reduced energy and water consumption: Single-use bioprocessing systems reduce the need for water and electricity compared to stainless steel systems. Manufacturing facilities can save time and resources on sanitation because of the disposable nature of bioprocessing systems.
5. Limiting the risk of cross-contamination: Reduced potential for contamination is a top priority in bioprocessing. Single-use equipment helps reduce the risk of contamination because it involves discarding and replacing the whole product flow channel between processing steps to prevent contamination from one batch to the next.