Tube sealing and fusing systems

Aseptic procedures help prevent contamination by avoiding the transfer of unwanted cells and microorganisms. These methods combine environmental control, operator protocols, and sterilizing equipment and media to assure product sterility.

Scientists in fields such as microbiology, medical research, and molecular biology use aseptic techniques to ensure process success and uniformity. Scientists that conduct cell-based processes must use aseptic procedures to decrease the danger of contamination by pathogens and different types of cells. Aseptic processing is crucial in upstream and downstream processing for biopharmaceutical manufacturing as well as for filling drug products.

Bioprocessing involves various steps and fluid transfers that must be done aseptically. Sealers and fusers are used to weld sections of tubing to connect or seal them.

Aseptic sealers and fusers

The connection of single-use components to make a usable assembly is a vital step and a risk during application. Aseptic sealers and fusers are crucial for connecting liquid handling components.

Biomanufacturing processes require the right tools to ensure reliable connections between components. Our aseptic sealers and fusers help create sterile connections between thermoplastic tubing elements. Automation, for example in the ReadyToProcess™ Tube Sealer , eliminates the need for human contact and limits the probability of contamination.

Aseptic and sterile sealing machines come in varying designs with unique specifications. When buying a tube sealer or fuser, consider flexibility and portability. Aseptic tube welding and sealing processes facilitate aseptic operation without the need for environmental control devices.

Aseptic sealers and fusers FAQs

Here are some answers to commonly asked questions about aseptic sealers and fusers.

How do aseptic sealers and fusers work?

Sterile tube sealers and fusers enable researchers and biomanufacturers to link two tubing lines while keeping the fluid channel sterile. Each tubing line gets pre-attached to a connector end with a detachable membrane or valve barrier for connection to another connector end.

Therefore, the process line remains closed and sterile even before the connection. Sterile connectors are designed to connect one processing stream to another, such as a container to a sampling line, media to a product vessel, or a filtration assembly to a filling.

What aseptic sealers and fusers does Cytiva offer?

We offer sterile tube fusers for welding dry thermoplastic tubing in aseptic operations without the need for a laminar flow cabinet, as well as sterile tube fusers for wet aseptic operations. We also offer the ReadyToProcess™ Tube Sealer, fully automated, portable single-use device for sealing tubing in a sterile operation.