Capto™ Blue affinity chromatography resin

Capto Blue affinity resin with Cibacron Blue ligand has outstanding pressure and flow properties, allowing rapid processing of large sample volumes of albumin and other proteins.

Pack size

5 L

25 mL

500 mL

Capto Blue resin

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Price includes standard shipping and handling

Overview

Capto Blue affinity resin with Cibacron Blue ligand has outstanding pressure and flow properties, allowing rapid processing of large sample volumes of albumin and other proteins.

Excellent chemical stability ensures tolerance of harsh solvents used in repeated cleaning-in-place and sanitization procedures.
Capto Blue can be autoclaved repeatedly.
Highly rigid agarose base matrix allows high flow rates and processing of large sample volumes with no reduction in binding capacity.
Ligand functionality can be modified through the use of appropriate buffer salts and buffer conductivity to increase selectivity for desired targets.
Excellent choice for the removal or purification of proteins at both laboratory and process scales.
Resin fulfills industrial demands for security of supply, robust performance, and regulatory support.

Capto Blue applications

Uses of Capto Blue and Capto Blue (high sub):

capture of human serum albumin (HSA)
purification of HSA fusion proteins
purification of blood coagulation factors, enzymes, and recombinant proteins

Improvements compared with predecessor resin

Developed from Blue Sepharose 6 Fast Flow, Capto Blue products are more chemically stable and have a more rigid agarose base matrix than their predecessor. These improvements allow the use of higher flow rates and larger sample volumes, enabling increased throughput and improved process economy.