Capto™ Butyl ImpRes hydrophobic interaction chromatography resin
Capto Butyl ImpRes is a HIC resin for the intermediate and polishing steps in a downstream purification process.
Pack size
Overview
- High-resolution purification based on Capto ImpRes base matrix with a traditional HIC ligand and smaller average particle size.
- Flexible process design due to a large operational window of flow velocities and bed heights.
- Higher throughput compared with Capto Butyl might enable improved productivity and process economy.
- Excellent chemical stability.
- Resin fulfills industrial demands for security of supply, robust performance, and regulatory support.
Get improved flexibility and productivity
Capto Butyl ImpRes is a bioprocess chromatography resin developed for large-scale purification of biopharmaceutical proteins. Based on the well-established Capto base matrix with traditional butyl ligands, this high-resolution resin provides many opportunities for improved productivity and straightforward process development.
Smaller particle size
By combining the high-flow characteristics of Capto resin with a smaller particle size, Capto Butyl ImpRes deliver both excellent pressure/flow properties and resolution. The ability to run at higher flow velocities and higher bed heights increases flexibility in process design and facilitates increased productivity.
Prepacked columns and other formats
Capto Butyl ImpRes resin is available in the following formats:
Process development scale: prepacked
- HiScreen Capto Butyl ImpRes columns, optimized for method and process development.
- PreDictor Capto Butyl ImpRes filter plates, 96-well plates for high-throughput screening or process development.
- PreDictor Capto Butyl ImpRes RoboColumn™ units, miniaturized columns for high-throughput process development.
- f(x) column, prepacked and precharacterized chromatography column for fast and accurate mechanistic modeling.
Lab scale: prepacked for manual purification
HiTrap Capto Butyl ImpRes columns, for easy use with a syringe, peristaltic pump, or chromatography system.
Lab scale: prepacked for automated purification and analysis
HiTrap Capto Butyl ImpRes columns, for easy use with a syringe, peristaltic pump, or chromatography system.
Process characterization: resin kits
Process Characterization Kit Capto Butyl ImpRes, designed for studying the potential impact that resin ligand density might have on the process outcome.
Process-scale purification: prepacked
ReadyToProcess Capto Butyl ImpRes columns, 1 L and larger columns for clinical manufacturing that minimize the need for cleaning and cleaning validation.
