Capto™ MMC ImpRes resin prepacked in ReadyToProcess™ single-use columns
A weak cation exchange multimodal resin column for high-resolution polishing of mAbs and other biomolecules.
Pack size
Overview
These ReadyToProcess chromatography columns are prepacked with Capto MMC ImpRes chromatography resin and are excellent high-resolution polishing of mAbs and other biomolecules. ReadyToProcess columns are validated high-performance bioprocessing columns that are supplied prepacked and ready for use.
- High yields achieved through the high-resolution beads and selectivity of the ligand.
- Efficient removal of aggregates, viruses, and main contaminants in MAb processes.
- Enables use of a platform approach to MAb process development.
- Displays a broad pH/salt operational window.
- Suitable for polishing of antibody fragments.
About Capto MMC ImpRes
The weak cation exchange multimodal ligand enables high selectivity in a broad pH/salt window compared with traditional ion exchangers, which allows the use of Capto MMC ImpRes in a variety of process conditions to solve challenging purification problems. The multimodal cation exchanger ligand of Capto MMC ImpRes is immobilized to the base matrix and interacts with the target molecule through multiple types of interactions.
Suitable for sensitive MAbs and other biomolecules
Capto MMC ImpRes can be used for initial or final polishing steps in MAb purification processes, as well as for the polishing of antibody fragments such as domain antibodies (DAbs). The wide window of operation for conductivity and/or pH simplifies the process as conditioning after the protein A step can be omitted. When working with sensitive MAbs, the wide window of operation simplifies optimization of conditions.
Product specifications
