Capto™ Octyl hydrophobic interaction chromatography resin
Designed to enable high-throughput capture and intermediate purification steps for a wide range of biomolecules, Capto Octyl offers flexible process design options.
Pack size
Overview
- Designed to enable high-throughput capture and intermediate purification steps for a wide range of biomolecules, Capto Octyl offers flexible process design options.
- Intermediate and capture purification resin based on Capto base matrix with a traditional octyl HIC ligand.
- Flexible process design due to a large operational window of flow velocities and bed heights.
- Excellent chemical stability.
- Resin fulfills industrial demands for security of supply, robust performance, and regulatory support.
Useful for large-scale processes
Capto Octyl is a bioprocess chromatography resin developed for large-scale purification of biopharmaceutical proteins. Based on the well-established Capto base matrix and with traditional octyl group ligands, it provides many opportunities for improved productivity and straightforward process development.
This chromatography resin is part of the high-flow agarose Capto product line.
Enables improved productivity
The high-flow characteristics of Capto Octyl resin deliver excellent pressure-flow properties enabling enhanced productivity compared with Octyl Sepharose 4 Fast Flow resin. The ability to run at higher flow rates and higher bed heights also increases flexibility in process design.
Prepacked columns and other formats
Capto Octyl is available in the following formats:
Process development scale – prepacked
- PreDictor Capto Octyl filter plates – 96-well plates for high-throughput screening or process development
- PreDictor Capto Octyl RoboColumn units – miniaturized columns for high-throughput process development
- HiScreen Capto Octyl columns – optimized for method and process development
Lab/research scale – prepacked for manual purification
HiTrap Capto Octyl columns – for easy use with a syringe, peristaltic pump, or chromatography system
Lab/research scale – prepacked for automated purification and analysis
HiTrap Capto Octyl columns – for easy use with a syringe, peristaltic pump, or chromatography system
Process scale purification: prepacked
ReadyToProcess Capto Octyl columns, 1 L and larger columns for clinical manufacturing that minimize the need for cleaning and cleaning validation
