Pall™ Pegasus™ Prime membrane in Microdisc capsules

Pegasus™ Prime membrane in Microdisc capsules, part of our Pall filtration portfolio, are for the confirmation and validation of performance at a small scale using minimal volumes of process fluid and virus spike preparations.

A combination of high log reduction value (LRV), high throughput, and high flow in all monoclonal antibody (mAb) solutions, Pegasus™ Prime virus filters deliver an economic virus filtration solution with a small footprint for easy integration into single-use and automated processes.

For feed streams with high levels of fouling protein aggregates, Pegasus Prime can be combined with Pegasus Protect prefilters for high parvovirus retention, capacity and flux.

Pegasus™ Prime membrane in Microdisc capsules are available gamma-sterilized or suitable for autoclave.

Features and benefits

Sterility

Autoclavable

Gamma irradiated

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Overview

Pegasus™ Prime membrane in Microdisc capsules, part of our Pall filtration portfolio, are for the confirmation and validation of performance at a small scale using minimal volumes of process fluid and virus spike preparations.

A combination of high log reduction value (LRV), high throughput, and high flow in all monoclonal antibody (mAb) solutions, Pegasus™ Prime virus filters deliver an economic virus filtration solution with a small footprint for easy integration into single-use and automated processes.

For feed streams with high levels of fouling protein aggregates, Pegasus Prime can be combined with Pegasus Protect prefilters for high parvovirus retention, capacity and flux.

Pegasus™ Prime membrane in Microdisc capsules are available gamma-sterilized or suitable for autoclave.

Features and benefits

>4 Log reduction value for mammalian parovirus
Robust capacity and high flow for small filtration footprint and short processing times
Stable performance in a broad process design space
Robust retention maintained during process interruptions
Suitable for continuous processing at low flux and pressure
Predictable performance at all scales for simple process development
Easy to install, use and integrity test
Flexible options to suit all facilities

Materials of construction

Filter membrane: Polyethersulfone
Capsule hardware: Polypropylene
Support substrate: Polyester

Retention ratings

Virus: > 4 log reduction value with mammalian parvoviruses

Effective filter area (EFA) (nominal)

2.8 cm²

Operating parameters

Maximum temperature: 40°C
Maximum pressure: 3.1 bar (45 psi)*
Maximum differential pressure: 3.1 bar (45 psi)*
*up to 12 hours at 25°C; up to 6 hours at 40°C

Shelf life

3 years for gamma-sterile version

1 year for autoclavable version, shelf life studies ongoing.

Liquid flow v differential pressure (typical)

1.4 – 2.6 mL/min at 2.1 bard, water at 20°C

Dimensions (nominal)

Length: 21 mm
Diameter: 29 mm

Connection type

Female Luer-Lock inlet, male slip luer outlet