PreDictor™ MabSelect prepacked 96-well plates
A BioProcess protein A resin for mAb capture from large sample volumes, in a prepacked 96-well plate for high-throughput process development (HTPD).
Chromatography resin volume/well
Overview
- Supports high-throughput process development (HTPD) by allowing parallel screening of chromatographic conditions using a 96-well plate format.
- Allows fast and efficient evaluation of parameters for binding/wash/elution conditions, and resins benchmarking.
- Results show good correlation with data obtained by column chromatography.
- Each well is prefilled with defined amounts of Cytiva BioProcess chromatography resins.
- Can be used with centrifugation or vacuum, manually or in automated robotic systems.
- Assist software supports the PreDictor workflow from set-up of experimental design to data evaluation.
About MabSelect resin
MabSelect is a BioProcess affinity resin for capturing monoclonal antibodies (mAbs) from large sample volumes.
The resin is based on a highly cross-linked agarose matrix with a recombinant protein A ligand. This ligand is engineered to favor an oriented coupling resulting in an affinity resin with enhanced binding capacity for IgG.
The hydrophilic nature of the base matrix ensures low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool. MabSelect is optimized for high capacity, throughput and to deliver a product pool that is high in purity and yield.
About PreDictor MabSelect plates
PreDictor plates are disposable, 96-well filter plates for parallel screening of resins and chromatographic conditions such as binding, wash, and elution conditions.
- Screen different chromatography resins simultaneously using dedicated screening plates, or more thoroughly using plates containing a single resin.
- Different applications require different amounts of resins in the wells, and we offer a wide range of PreDictor plates containing different chromatography resins at different volumes.
- Data generated using PreDictor plates show good correlation with data from chromatography columns, making the plates an excellent tool for initial screening of process conditions.
Assist software supports the PreDictor workflow from set-up of experimental design to data evaluation.
Prepacked columns and other formats
MabSelect resin is available in the following formats:
Bulk resin
Loose MabSelect resin in bottles for batch purification or packing your own columns.
Process development scale – prepacked
HiScreen MabSelect columns – optimized for method and process development.
Lab/research scale – prepacked for manual purification
HiTrap MabSelect columns – for easy use with a syringe, peristaltic pump, or chromatography system.
Lab/research scale – prepacked for automated purification and analysis
HiTrap MabSelect columns – for easy use with a syringe, peristaltic pump, or chromatography system.
Process scale purification – prepacked
ReadyToProcess MabSelect NS columns – 1 L and larger columns for clinical manufacturing that avoid the need for cleaning and cleaning validation.
Learn about MabSelect, prepacked HiTrap MabSelect, HiScreen MabSelect, ReadyToProcess MabSelect columns or PreDictor Robocolumns MabSelect
