“Cytiva’s solutions provide us with the flexibility and modularity to offer our customers tailored manufacturing. With the addition of Cytiva’s robotic aseptic filling solutions, we are truly an end-to-end, single point of contact CDMO, reducing overall complexity, cost, and time to the product innovators.”
- Mark Bamforth, Executive Chair and CEO, Arranta Bio
mRNA purification removes enzymes, remaining nucleotides, plasmid DNA, and defective mRNA. New emerging technologies like Fibro chromatography, currently available for mAb purification, are in development for molecules such as DNA plasmids and mRNA.
Lipid nanoparticles (LNPs) are a key technology for making mRNA vaccines and other genetic medicines. The purified mRNA therapeutic is formulated in LNPs as a drug delivery vehicle. Core chromatography can be used to further remove impurities.