Single-cell sequencing

A single-cell sequencing future

Single-cell sequencing is enabling scientists to delve ever deeper into understanding cell biology. This understanding is extending beyond genomics to include proteomics and metabolomics—collectively called Omics.

Whitepaper: Single-cell sequencing challenges and opportunities

Recent technological advancements have made single-cell sequencing an increasingly powerful tool for diagnosis, treatment response prediction, and treatment selection for cancer. The high cost and technical challenges of this technology initially restricted single-cell sequencing to just a few laboratories. Today, however, tens of thousands of individual cells from a single sample or patient can be analyzed, giving researchers an unprecedented opportunity to understand individual cell populations and their behavior in diseased tissue.

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Tissue disaggregation for single cell sequencing

Improving the efficiency and consistency of tissue disaggregation

Current tissue disaggregation techniques are manual and time-consuming, with the output dependent on the experience of the operator. The yield and quality of produced cells can vary between user and environment. The VIA Extractor™* tissue disaggregator for Omics applications offers a closed, semi-automated solution, reliably reducing sample-to-sample variation.

Find out how gentle, automated tissue digestion optimizes cell viability for sensitive downstream processes.

*For research use only (RUO). Not for diagnostic use.

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VIA Extractor tissue digester open view with bag right

Comparing tissue dissociation for single-cell RNA sequencing analysis

Careful handling and processing of human or animal tissue sample is critical to minimize any process-induced effects that may skew results of single cell analyses. Here, we investigate the ability of the VIA Extractor™* tissue disaggregator to generate high quality single cell suspensions from fresh tissue for use in scRNA-seq analysis.

*For research use only (RUO). Not for diagnostic use.

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