ÄKTAexplorer
ÄKTAexplorer was discontinued in 2010 and is replaced with ÄKTA avant. We offer limited service upon availability of parts from our suppliers.
ÄKTApurifier
ÄKTApurifier was discontinued in 2014 and is replaced with ÄKTA pure. We offer limited service upon availability of parts from our suppliers.
ÄKTAmicro
ÄKTAmicro was discontinued in 2014 and is replaced with ÄKTA pure with microgram scale purification flow path. We offer limited service upon availability of parts from our suppliers.
ÄKTAprime plus
ÄKTAprime plus has been discontinued in 2019 and is replaced with ÄKTA go. Service of ÄKTAprime plus is available until June 2024. After this date, we offer limited service upon availability of parts from our suppliers.
ÄKTAxpress
ÄKTAexpress has been discontinued in 2018. Service of ÄKTAxpress is available until June 2024. After this date, we offer limited service upon availability of parts from our suppliers.
ÄKTA start | ÄKTA go | ÄKTA pure | ÄKTA avant | |
Easy transition from manual to automated protein purification/education in protein purification | Achieve desired purity with ease in routine purifications—make the most of valuable bench/cold room space | Flexibility in research—match current and future purification challenges | Productivity in process development—fast and secure development of purification processes | |
Application | ||||
Automated and reproducible protein purification including support for gradient elution | ✔ | ✔ | ✔ | ✔ |
Support for affinity chromatography, ion exchange chromatography, and multimodal (mixed mode) chromatography | ✔ | ✔ | ✔ | ✔ |
Support for size exclusion chromatography | Limited capabilities | ✔ | ✔ | ✔ |
Support for hydrophobic interaction chromatography | Limited capabilities | ✔ | ✔ | |
Software compatible with regulatory requirements, e.g., GLP, GMP | ✔ | ✔ | ✔ | |
Microscale purification | ✔ | |||
Automatic buffer preparation including pH scouting | ✔ | |||
Scale-up, process development | Optional | ✔ | ||
Method development and optimization using design of experiments (DoE) | Optional | ✔ | ||
Automatic resin or column scouting | Optional | ✔ | ||
Automatic multistep purification | Optional | Optional | ||
Advanced automation including external equipment | Optional | Optional | Optional | |
Flow rate (mL/min) | 0.5 to 5.0 | 0.01 to 25.0 | 0.001 to 25.0/ 0.01 to 150 | 0.001 to 25.0/ 0.01 to 150 |
Max. operating pressure (MPa, bar, psi) | 0.5, 5.0, 72.5 | 5, 50, 725 | 20, 200, 2900/5, 50, 725 | 20, 200, 2900/5, 50, 725 |