NHS-Activated Sepharose 4 Fast Flow is used to couple ligands with primary amino groups to create affinity chromatography resins. It is particularly suited for immobilizing small protein and peptide ligands in process-scale applications.
NHS-Activated Sepharose 4 Fast Flow resin
High-performance NHS-activated resin for efficient covalent coupling of proteins, peptides, or other ligands.
NHS-Activated Sepharose 4 Fast Flow resin
High-performance NHS-activated resin for efficient covalent coupling of proteins, peptides, or other ligands.
Pack size
Overview
NHS-activated Sepharose 4 Fast Flow is a pre-activated agarose matrix that increases the choice of coupling chemistries available. Suitable for coupling amino-containing smaller proteins and peptides.
- NHS pre-activated resin for coupling of small amino-containing proteins and peptides in process-scale applications
- High level of pre-activation gives a high degree of substitution of the selected ligand
- NHS coupling method results in chemically stable ligand attachment
- BioProcess resin supported for industrial applications
NHS-activated Sepharose 4 Fast Flow is composed of cross-linked 4% agarose beads, NHS activated for coupling amino-containing proteins and peptides in process-scale applications. NHS (N-hydroxysuccinimide) coupling forms a chemically stable amide bond with ligands containing primary amino groups.
This resin provides a spacer arm to the coupled ligand and is therefore particularly suitable for immobilising smaller protein and peptide ligands.
NHS-activated Sepharose 4 Fast Flow is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess resins range, NHS-activated Sepharose 4 Fast Flow meets industrial demands with security of supply and comprehensive technical and regulatory support