Pall™ Pegasus™ Prime membrane in Microdisc capsules
Pegasus™ Prime membrane in Microdisc capsules, part of our Pall filtration portfolio, are for the confirmation and validation of performance at a small scale using minimal volumes of process fluid and virus spike preparations.
A combination of high log reduction value (LRV), high throughput, and high flow in all monoclonal antibody (mAb) solutions, Pegasus™ Prime virus filters deliver an economic virus filtration solution with a small footprint for easy integration into single-use and automated processes.
For feed streams with high levels of fouling protein aggregates, Pegasus Prime can be combined with Pegasus Protect prefilters for high parvovirus retention, capacity and flux.
Pegasus™ Prime membrane in Microdisc capsules are available gamma-sterilized or suitable for autoclave.
Features and benefits
Pall™ Pegasus™ Prime membrane in Microdisc capsules
Pegasus™ Prime membrane in Microdisc capsules, part of our Pall filtration portfolio, are for the confirmation and validation of performance at a small scale using minimal volumes of process fluid and virus spike preparations.
A combination of high log reduction value (LRV), high throughput, and high flow in all monoclonal antibody (mAb) solutions, Pegasus™ Prime virus filters deliver an economic virus filtration solution with a small footprint for easy integration into single-use and automated processes.
For feed streams with high levels of fouling protein aggregates, Pegasus Prime can be combined with Pegasus Protect prefilters for high parvovirus retention, capacity and flux.
Pegasus™ Prime membrane in Microdisc capsules are available gamma-sterilized or suitable for autoclave.
Features and benefits
Sterility
Overview
Pegasus™ Prime membrane in Microdisc capsules, part of our Pall filtration portfolio, are for the confirmation and validation of performance at a small scale using minimal volumes of process fluid and virus spike preparations.
A combination of high log reduction value (LRV), high throughput, and high flow in all monoclonal antibody (mAb) solutions, Pegasus™ Prime virus filters deliver an economic virus filtration solution with a small footprint for easy integration into single-use and automated processes.
For feed streams with high levels of fouling protein aggregates, Pegasus Prime can be combined with Pegasus Protect prefilters for high parvovirus retention, capacity and flux.
Pegasus™ Prime membrane in Microdisc capsules are available gamma-sterilized or suitable for autoclave.
Features and benefits
- >4 Log reduction value for mammalian parovirus
- Robust capacity and high flow for small filtration footprint and short processing times
- Stable performance in a broad process design space
- Robust retention maintained during process interruptions
- Suitable for continuous processing at low flux and pressure
- Predictable performance at all scales for simple process development
- Easy to install, use and integrity test
- Flexible options to suit all facilities
Materials of construction
Filter membrane: Polyethersulfone
Capsule hardware: Polypropylene
Support substrate: Polyester
Retention ratings
Virus: > 4 log reduction value with mammalian parvoviruses
Effective filter area (EFA) (nominal)
2.8 cm2
Operating parameters
Maximum temperature: 40°C
Maximum pressure: 3.1 bar (45 psi)*
Maximum differential pressure: 3.1 bar (45 psi)*
*up to 12 hours at 25°C; up to 6 hours at 40°C
Shelf life
3 years for gamma-sterile version
1 year for autoclavable version, shelf life studies ongoing.
Liquid flow v differential pressure (typical)
1.4 – 2.6 mL/min at 2.1 bard, water at 20°C
Dimensions (nominal)
Length: 21 mm
Diameter: 29 mm
Connection type
Female Luer-Lock inlet, male slip luer outlet
