Lipid nanoparticle instruments and reagents

Lipid nanoparticle solutions are designed to accelerate next-generation drug delivery. Explore our comprehensive portfolio of lipid nanoparticle instruments, reagents, and workflow tools designed for formulation, characterization, and scale-up. From LNP formulation systems to precisely formulated kits for RNA delivery, we provide the products you need to optimize stability, encapsulation efficiency, and reproducibility for mRNA and other nucleic acid therapeutics. Start building your LNP workflow today – discover LNP solutions that streamline development and enable scalable success.

Showing 1-17 of 17 items

CD34+ HSC LNP kits

The CD34+ HSC LNP kit is an LNP reagent mix optimized for the delivery of mRNA or Cas9 mRNA/sgRNA into CD34+ HSCs. This reagent enables researchers to establish a clinically relevant and scalable method at the discovery and preclinical scale for ex vivo gene delivery and editing. CD34+ HSC LNP kit offers the following benefits:

CD34+ HSC LNP kit, 100 µL

1003000

In stock–16 available

705.00 USD

CD34+ HSC LNP kit, 2 mL

1005000

In stock–6 available

4,000.00 USD

Cytiva CD34+ HSC LNP kit, 100 uL, with Cartridges

29874065

Stock on request

952.00 USD

GenVoy-ILM™ reagents and kits

GenVoy-ILM™ reagents are LNP reagents that enable the production of RNA-LNPs using the NanoAssemblr™ Ignite™ and Ignite+™ instruments. The resulting LNPs formed by mixing GenVoy-ILM™ and nucleic acids using Ignite™ and Ignite+™ instruments feature a homogeneous core structure. This reagent has been designed to:

Formulation buffer, 20 mL

1002775

In stock–14 available

379.00 USD

GenVoy-ILM™ reagent, 2 mL

1002763

In stock–17 available

3,749.00 USD

GenVoy-ILM™ reagent, 5 mL, Ignite

1002769

In stock–51 available

9,373.00 USD

GenVoy-ILM™ T cell kits for mRNA

GenVoy-ILM™ T cell Kit for mRNA is a lipid nanoparticle (LNP) reagent mix optimized for the delivery of mRNA or CRISPR Cas9 mRNA with gRNA into human primary T cells using LNPs prepared on the NanoAssemblr™ Spark™ and Ignite™ systems.

GenVoy-ILM T Cell Kit for mRNA, Spark with Cartridges

29874064

Stock on request

920.00 USD

GenVoy-ILM™ T cell Kit for mRNA

1000701

In stock–9 available

672.00 USD

GenVoy-ILM™ T cell Kit for mRNA, Ignite™, 3 mL

1001144

In stock–7 available

6,000.00 USD

Hepato9 mRNA transfection kit

Hepato9 mRNA kit is a lipid nanoparticle (LNP) reagent that enables the rapid production of RNA-LNPs using the NanoAssemblr™ Spark™ instrument and is optimized for the in vitro delivery of these nanoparticles.

NanoAssemblr Spark Kit - Hepato9 mRNA - 20 ug (2x) with Cartridges

29873659

Stock on request

1,043.00 USD

NanoAssemblr™ Blaze cartridges and tubing kits

NanoAssemblr™ Blaze cartridges and tubing kits are validated for single-use, reducing the risk of cross-contamination during process development of LNP formulations. Starting June 2025, customers can purchase the new NxGen™ Blaze cartridges for the NanoAssemblr™ Blaze nanoparticle formulation system and will have the option to reuse them.

NanoAssemblr™ Blaze™ 400 Cartridge

1000458

In stock–58 available

469.00 USD

NanoAssemblr™ Blaze™ 400D Cartridge

1000459

In stock–59 available

575.00 USD

NanoAssemblr™ Blaze™ 500 Cartridge

1000460

In stock–53 available

469.00 USD

NanoAssemblr™ Blaze nanoparticle formulation system

The NanoAssemblr™ Blaze and Blaze+ systems streamline the process development of lipid nanoparticle (LNP) formulation, enabling the efficient scaling from early research through preclinical and early clinical development. With flexible volume options and a closed system environment, these systems support early chemistry, manufacturing, and control (CMC) studies and large-scale protocol development for upstream and downstream operations, providing valuable insights into processes and consumables required for GMP manufacturing.

NanoAssemblr™ Blaze™ System

NIB0055

Stock on request

On request

NanoAssemblr™ Blaze+™ System Upgrade

NIB0061

Stock on request

On request

NanoAssemblr™ commercial formulation system

The NanoAssemblr™ commercial formulation system simplifies GMP manufacturing of LNPs through an automated workflow of priming, calibration, formulation, and in-line dilution and a single-use flow path that enables efficient changeover.

NanoAssemblr™ commercial formulation system

1002276

Stock on request

On request

NanoAssemblr™ commercial formulation system flow kits

The NanoAssemblr™ commercial formulation system flow kit includes the NxGen™ cartridge, pump heads, flow meters, and flow path and can be installed in less than 60 minutes. The flow kit is available as a single-use manufacturing flow kit and a limited, multi-use development flow kit.

NxGen™ commercial development flow kit 12 L/h

1002277

Selling fast–1 available

13,400.00 USD

NxGen™ commercial development flow kit 48 L/h

1002278

Stock on request

13,400.00 USD

NxGen™ commercial manufacturing flow kit 12 L/h

1002279

Stock on request

On request

NanoAssemblr™ GMP System fluid paths

The fluid path for the NanoAssemblr™ GMP System includes the NxGen™ cartridge, pre-assembled connective tubing, and pump heads, reducing the risk of cross-contamination between drug products and batches. It is available as a single-use fluid path for GMP manufacturing and a multi-use fluid path for research-use-only (RUO) with either the NxGen™ 400D or NxGen™ 500D cartridge.

NanoAssemblr™ GMP Fluid Path with NxGen™ 400D

1000438

Stock on request

On request

NanoAssemblr™ GMP Fluid Path with NxGen™ 500D

1000440

Stock on request

On request

NanoAssemblr™ RUO Fluid Path with NxGen™ 400D

1000442

Stock on request

12,700.00 USD

NanoAssemblr™ GMP System for nanoparticle formulation

The NanoAssemblr™ GMP System is a complete, ready-to-use formulation system for the clinical development of LNPs. NxGen™ technology minimizes process development during scale-up and the single-use fluid path enables the rapid production of Phase I and II nanomedicine drug products.

NanoAssemblr™ GMP System

1000453-DUMMY

Stock on request

On request

NanoAssemblr™ Ignite and Ignite+ cartridges

Each cartridge is powered by NxGen™ technology, an advanced mixing architecture that uses toroidal structures within the flow path to maintain steady, consistent mixing conditions. This consistency enables effective transfer of critical process parameters (CPPs) when scaling with our NanoAssemblr™ family of formulation systems, all built with the same advanced NxGen™ technology. This unified design streamlines process redevelopment, reduces risk, and builds confidence in scale-up.

NxGen™ 500 cartridges (pack of 100)

1001398

In stock–12 available

16,200.00 USD

NxGen™ 500 cartridges (pack of 50)

1001397

In stock–51 available

10,700.00 USD

NxGen™ 500D cartridges (pack of 25)

1001399

In stock–20 available

7,725.00 USD

NxGen™ 500D cartridges (pack of 50)

1001400

In stock–11 available

12,200.00 USD

NxGen™ cartridges (pack of 100)

NIN0061

In stock–33 available

6,650.00 USD

NxGen™ cartridges (pack of 200)

NIN0062

In stock–57 available

9,972.00 USD

NxGen™ dilution cartridges (pack of 100)

NIN0064

In stock–16 available

9,972.00 USD

NxGen™ dilution cartridges (pack of 50)

NIN0063

In stock–33 available

6,650.00 USD

NanoAssemblr™ Ignite and Ignite+ nanoparticle formulation systems

The NanoAssemblr™ Ignite and Ignite+ systems enable scalable, reproducible, and easy-to-use formulation of lipid nanoparticles (LNPs) for preclinical genomic medicine development.

NanoAssemblr Ignite Training Kit with GenVoy-ILM (no payload)

29873661

Stock on request

733.00 USD

NanoAssemblr™ Ignite+™ instrument

1001413

Stock on request

On request

NanoAssemblr™ Ignite™ instrument

NIN0001

Stock on request

On request

NanoAssemblr™ Ignite heating packages

The NanoAssemblr™ Ignite and Ignite+ systems are designed for seamless operation with metal sleeve inserts called heating packages. These metal sleeves, strategically placed around the syringe, ensure optimal thermal contact between the syringe heaters of the system and syringes of varying sizes.

NanoAssemblr™ Ignite+ heating controller package

1001403

Selling fast–2 available

8,783.00 USD

NanoAssemblr™ Ignite+ heating inserts package

1001404

Selling fast–3 available

2,196.00 USD

NanoAssemblr™ Ignite heating inserts package

NIN0068

Selling fast–3 available

2,054.00 USD

NanoAssemblr™ Spark™ cartridges

NanoAssemblr™ Spark™ cartridges are equipped with NxGen™ mixing technology for use on the NanoAssemblr™ Spark™ systems for nanoparticle formulation.

NanoAssemblr Spark Cartridges - 20 Pack

NIS0009

In stock–32 available

1,040.00 USD

NanoAssemblr Spark Cartridges - 80 Pack

NIS0013

In stock–46 available

3,759.00 USD

NanoAssemblr™ Spark™ nanoparticle formulation system

The NanoAssemblr™ Spark™ nanoparticle formulation system enables the production of nanoparticle formulation in volumes ranging from 25 – 250 μL, ideal for discovery and screening that involves scarce or expensive nucleic acids and nanoparticle excipients.

Instrument training for NanoAssemblr™ Spark™

NOS0011

Stock on request

4,770.00 USD

NanoAssemblr Spark Demo Kit - mRNA with Cartridges

29873660

Stock on request

503.00 USD

NanoAssmblr™ Spark™ instrument

NIS0001

Selling fast–1 available

40,500.00 USD

Neuro9 siRNA kits

Neuro9 siRNA kits are lipid nanoparticle (LNP) reagents that enable the production of siRNA-LNPs using the NanoAssemblr™ Spark™ instrument. siRNA-LNP generated using the Neuro9 siRNA transfection kit are optimized for the delivery of these nanoparticles into rat neurons.

NanoAssemblr Spark Kit - Neuro9 siRNA - 2 nmol (2x) with Cartridges

29873655

Stock on request

1,043.00 USD

NanoAssemblr Spark Kit - Neuro9 siRNA - 5 nmol with Cartridges

29873656

Stock on request

1,043.00 USD

RNA delivery LNP kit

The RNA delivery LNP kit for the NanoAssemblr™ Ignite™ and Ignite+™ systems offers ready–to–use ionizable lipid mix and buffers to fast-track payload screening and RNA drug delivery validation, progressing lead candidates quickly through preclinical studies accelerating clinical evaluation.

RNA delivery LNP kit, 3 mL

1002569

In stock–10 available

4,200.00 USD

RNA delivery LNP kit, 6 mL

1002471

In stock–10 available

7,980.00 USD

Showing 1-17 of 17 items

Frequently asked questions

How do I choose the right LNP formulation system?

Select a system based on your development stage and throughput needs. Early research often uses benchtop flow systems, while scale-up requires advanced platforms with single-use cartridges for GMP compliance. Consider factors like mixing precision, scalability, and ease of cleaning.

Are these instruments suitable for GMP manufacturing?

Yes, many LNP systems are designed for GMP environments. They feature single-use components, validated processes, and documentation to support regulatory requirements. Check product specifications for compliance certifications before purchase.

Can I scale up LNP production with these tools?

Yes, these systems support seamless scale-up from research to commercial manufacturing. Modular designs and single-use cartridges simplify transitions while maintaining process integrity.

Do you offer guidance for LNP formulation optimization?

We provide technical resources and application notes to help optimize LNP formulation. Our specialists can advise on reagent selection, process parameters, and scale-up strategies.

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Lipid nanoparticle instruments and reagents

Frequently asked questions