Upstream bioprocessing solutions and services to accelerate your research
Support for cell culture media and upstream process development plus pilot-scale and production-scale manufacturing. From high-quality cell culture products to scalable single-use systems, we can help you increase productivity, optimize protein quality, and simplify your operations...right from the start.
Bioprocessing strategies for current and new biotherapeutics
It’s an exciting time to be working at the forefront of medical innovation, as biomolecules expand beyond monoclonal antibodies (mAbs). If you’re looking for insights, products, training, or services, we’ve got solutions to help you accelerate progress on your molecules of choice including mRNA, oligos, cell and gene therapies, antibody variants, vaccines.
Intensify your upstream manufacturing process
How do you know if an intensification approach will give you advantages over your current upstream process? Try our Process Intensification App – simply enter in your process parameters and immediately see the potential impact.
- Cell culture and fermentation products – media, feeds, sera, buffers and process liquids, microcarriers, single-use fermentors, rocking and stirred-tank bioreactors
- Cell and gene therapy – start-to-finish solutions for industrialized cell therapy and vector manufacturing
- Downstream products – chromatography columns, resins, membranes, and systems
- Liquid preparation and management – easy to connect single-use components for robust mixing, easy handling, and convenient storage of bioprocess liquids
- Bioprocess filtration – single-use filters and systems for clarification, bioburden reduction, polishing, and concentration
- Cell line development – jump start your process with our GOCHO™ platform
- Cell Culture Media Development – discover how using DoE in custom cell culture media development can increase protein quality and quantity
- Rapid Response Production – quickly get small volumes of customized cell culture media, supplements, and reagents in bottles or single-use bags
- Analytical Services – spent media analysis, microbial testing, protein quality, quality control analysis, and stability studies
- Stability Services – real-time, accelerated and temperature excursion studies conducted using ICH guidelines in cGMP laboratory
- Manufacturing services – pre-clinical and clinical biologics CDMO services up to phase II
- Process development (PD) services – custom design of cell culture media and feeds plus other PD services
- Product quality support – certificates of analysis, safety data sheets, regulatory support, and labels
- Knowledge center – webinars, videos, articles, and tools
- Resource center – discover our online tools, recent articles, helpful handbooks, or enjoy a podcast
- News center – news, announcements, and blog posts
- Special offers – save on discounted HyClone™ cell culture products
- FAQs – cell culture media manufacturing frequently asked questions