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Enrich, purify, and screen nucleic acids and proteins

Choose separation technologies that allow flexibility for both sample type and target analyte.

Scientist handling Sera-Mag equipment - side view, close up, mask on, angled 2 (high res)

The key to successful biomolecule analysis

When analyzing biomolecules, you’ll likely need to enrich, clean up, and purify in order to detect them and get the required sensitivity. One day you might be doing antibody purification; the next you might be doing DNA extraction – and also extracting RNA and proteins from that same sample. So, it’s important to choose separation technologies that are flexible with both sample type and target analyte.

What’s hot in immunodiagnostics and where are we taking it

Protein enrichment

Capturing and isolating low-abundant proteins from thousands of other proteins can be challenging. Magnetic beads from Cytiva simplify enrichment of the target protein by immunoprecipitation or pull-down.

SP3 protein and peptide cleanup workflow.

Total protein analysis

To analyze total proteins by mass spectrometry, you must remove detergents, salts, and other contaminants. Do so quickly and efficiently with a technique called protein and peptide single-pot solid-phase-enhanced sample preparation (SP3). Sera-Mag™ SpeedBead Carboxylate-Modified Magnetic Particles are well suited for that.

Magnetic bead surface functionalization

Customize enrichment or purification technology

When off-the-shelf options aren’t available, our custom conjugation service can help. We can conjugate any of our protein sample preparation, labeling, and detection products, including Sera-Mag™ Magnetic Beads and Mag Sepharose™ Magnetic Beads. Choose your level of service – from completing complex conjugations and formulations to performing your quality control tests.

Tissues can be highly heterogeneous, making it challenging to link analyses from DNA, RNA and protein derived from different parts of the tissue. With TriplePrep, all data comes from the same tissue, allowing meaningful deduction of regulatory processes between the analytes

DNA, RNA and protein extraction from a single sample

If you’re studying the omics disciplines in parallel, use the TriplePrep Kit for DNA extraction – plus extraction of RNA and protein – all from the same tissue sample in a single workflow.