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Primer Support™ 5G for DNA and RNA Synthesis
Primer Support™ 5G products are the fifth generation solid supports for oligonucleotide synthesis from Cytiva.These high-loaded solid support products are optimized for synthesis of oligonucleotides with a length of up to 70 nucleotides.
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Overview
Primer Support™ 5G products are the fifth generation solid supports for oligonucleotide synthesis from Cytiva.These high-loaded solid support products are optimized for synthesis of oligonucleotides with a length of up to 70 nucleotides.
- High loading capacity: For synthesis of DNA and RNA oligonucleotides of up to 70 bases, a nucleoside loading of 350 μmol/g for DNA and 300 μmol/g for RNA can be used without compromising yield or purity.
- Cost efficient synthesis: The high nucleoside loading on Primer Support 5G allows forcost savings ascompared to our previous generations of solid supports
- Convenience and flexibility: UnyLinker can be used for DNA, 2’OMe RNA, or other oligonucleotides that are compatible with 8 hour cleavage conditions (e.g., DNA or 2’OMe), hence enabling stocking of one support.
The Primer Support 5G base particle is composed of cross-linked polystyrene and delivers higher crude purityand synthesis yield compared to previous generations of our solid supports. These benefits are most evidentfor synthesis of RNA oligonucleotides. This support is available derivatized with UnyLinker, DNA, or RNAnucleosides. Additional versions of Primer Support 5G or larger pack-sizes are available on custom basis. Theseproducts include the same regulatory support as the standard products. Samples of tailored versions of PrimerSupport 5G, for R&D use, is available via www.chemgenes.com. Alternatively, customized 3’ nucleosides, modifications or linker can be coupled to Primer Support 5G amino. Primer Support 5G has been proven inscalable processes from research to industrial scale1
Scalability
Primer Support 5G provides excellent scalability with proven consistency in purity and yield up to 1 molesynthesis scale1. Primer Support 5G is designed for the synthesizers and columns that Cytiva supplies. The ÄKTAoligosynt™, OligoPilot™, and OligoProcess™ hardware platforms range from synthesis at a 10 μmol scale toseveral moles. The application data shown in this data file was generated with predecessors of the current ÄKTA oligosynt synthesizer.
1 Data generated by Ionis Pharmaceuticals
Product specifications
Showing 32 products
Specs
Product
Quantity
Type
Availability
Price
28996429
1 mmol
DNA UnyLinker
In stock10 available
28996433
10 mmol
DNA nucleosides
In stock15 available
28996434
10 mmol
DNA UnyLinker
In stock15 available
28996440
1 mmol
RNA nucleosides
In stock9 available
28996441
1 mmol
RNA nucleosides
In stock7 available
28996442
1 mmol
RNA nucleosides
In stock6 available
28996444
10 mmol
RNA nucleosides
In stock9 available
28996445
10 mmol
RNA nucleosides
In stock9 available
28996425
1 mmol
DNA nucleosides
Selling fast5 available
28996426
1 mmol
DNA nucleosides
Selling fast5 available
28996427
1 mmol
DNA nucleosides
Selling fast5 available
28996428
1 mmol
DNA nucleosides
Selling fast4 available
28996430
10 mmol
DNA nucleosides
Selling fast4 available
28996431
10 mmol
DNA nucleosides
Selling fast2 available
28996432
10 mmol
DNA nucleosides
Selling fast2 available
28996446
10 mmol
RNA nucleosides
Selling fast4 available
28996447
10 mmol
RNA nucleosides
Selling fast3 available
29014617
100 mmol
DNA UnyLinker
Selling fast1 available
29014619
1 mmol
RNA nucleosides
Selling fast3 available
29099992
10 g
Amino
Selling fast3 available
28996443
1 mmol
RNA nucleosides
Stock on request
29014613
100 mmol
DNA nucleosides
Stock on request
29014614
100 mmol
DNA nucleosides
Stock on request
29014615
100 mmol
DNA nucleosides
Stock on request
29014620
10 mmol
RNA nucleosides
Stock on request
29025961
50 g
Amino
Stock on request
29100343
500 g
Amino
Stock on request
29138978
100 mmol
DNA nucleosides
Stock on request
29697584
100 mmol
RNA nucleosides
Stock on request
29697585
100 mmol
RNA nucleosides
Stock on request
29697586
100 mmol
RNA nucleosides
Stock on request
29697587
100 mmol
RNA nucleosides
Stock on request
Product availability is not guaranteed and subject to change.
