Low non-specific binding

The resin is based on a highly cross-linked agarose matrix with a recombinant protein A ligand. The ligand is engineered to favor an oriented coupling, resulting in an affinity resin with enhanced binding capacity for IgG. The hydrophilic nature of the base matrix ensures low levels of non-specific binding, leading to low levels of host cell-derived impurities in the elution pool. MabSelect resin is optimized for high capacity and throughput and delivers a product pool of high purity and yield.

Key benefits of ReadyToProcess columns include:

• Robust column design and validated packing methods enable consistent column performance.
• Standardized column formats allow reduced column cost and off-the-shelf availability for short delivery lead times.
• Cost-savings by eliminating the need for column preparation, packing, and validation procedures.
• Fulfills industrial demands for security of supply, robust performance, and regulatory support.

Learn about MabSelect, prepacked HiScreen MabSelect, HiTrap MabSelect, PreDictor MabSelect or PreDictor Robocolumns MabSelect