MabSelect PrismA™ resin is available for immediate delivery.

MabSelect PrismA™ affinity chromatography resin has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein A-derived ligand. This allows future demands in mAb purification to be met, including processing of many bispecific antibodies.

  • Enhanced dynamic binding capacity allows high mass throughput of processed mAb per resin volume unit.
  • Excellent alkaline stability enables efficient cleaning and sanitization using 0.5–1.0 M NaOH for improved process economy, bioburden control, and robustness.
  • Covered by a comprehensive security of supply program, including dual sources of the agarose base matrix and protein A ligand.
  • The PrismA protein A ligand is also available in HiTrap Fibro™ and HiScreen Fibro™ PrismA chromatography units for ultrafast purification of mAbs.
  • Easily measure protein A leakage using the PrismA ELISA kit specifically designed for use with MabSelect PrismA™ resins.

The enhanced alkaline stability of MabSelect PrismA™ also provides opportunities for more robust mAb purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bioburden control for continuous processes, which can be exposed to days or weeks of feed harvest.

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Product Product Name Price
17549805 MabSelect PrismA™, 10 L 10 L On Request
17549803 MabSelect PrismA™, 1 L 1 L 21,592.41 USD Add to cart


17549804 MabSelect PrismA™, 5 L 5 L On Request
17549801 MabSelect PrismA™, 25 mL 25 mL 2,092.37 USD Add to cart


17549802 MabSelect PrismA™, 200 mL 200 mL 6,275.89 USD Add to cart


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