Explore upstream

Xcellerex™ automated perfusion system

Single-use system for intensified cGMP manufacturing of preclinical and clinical material.

ReadyToProcess WAVE™ 25

A rocking bioreactor ideally suited to intensification of seed train operations.

Xcellerex™ XDR bioreactors

Single-use stirred tank bioreactors designed for scalability and robustness

Maximizing N-1 cell density to intensify your production bioreactor operation

The higher the inoculation cell density, the shorter the process duration in your production bioreactor needs to be. Learn how you can utilize Xcellerex™ APS to achieve cell densities of 179 MVC/mL to increase your production bioreactor productivity.

Read the application note here

Growth and viability for intensified N-1 perfusion processes - ReadyToProcess WAVE and Xcellerex APS

Developing a continuous large-scale perfusion cell culture process

Perfusion processes are truly continuous operations whereby proteins of interest are harvested over extended durations. This study demonstrates how this previously complex operation can be automated and simplified using Xcellerex™ APS.

Achieve up to 33% increase in your fed batch productivity with N-1 perfusion

By intensifying your seed train operations, you can reduce the production bioreactor duration. The result is a capacity increase with no additional production bioreactors required.

Additionally, inoculation of the N-1 bioreactor using a high-density cell bank can further compress the upstream process timeline.

Overview of conventional seeding process vs the intensified high-density seed process.

Learn more about intensification strategies across the entire workflow

This on-demand webinar gives practical examples of N-1 and N bioreactor intensification. In addition you can discover how to optimize your cell culture media when implementing intensified processes.

See the webinar for yourself